Results 71 to 80 of about 3,095,943 (305)

Analysis framework for the interaction between lean construction and building information modelling [PDF]

, 2009
Building with Building Information Modelling (BIM) changes design and production processes. But can BIM be used to support process changes designed according to lean production and lean construction principles? To begin to answer this question we provide
Dave, B, Koskela, LJ, Owen, RL, Sacks, R
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Dynamic response of plates on elastic foundation under eccentric impact load

MATEC Web of Conferences, 2017
In this study, nonlinear three-dimensional finite element analysis has been used to conduct a numerical investigation of the effect of applied impact load on the foundation based on sandy soil using the finite element method by ANSYS (Version 11 ...
Fattah Mohammed Y., Hamood Mohammed J., Abbas Sura A.   +2 more
doaj   +1 more source

The project of sports complex with gyms, sports hall and swimming pool with the study of holding elements of structure [PDF]

, 2019
In master thesis project, the project of sports complex with gyms, sports hall and swimming pool with the study of holding elements of structure the main structural elements of the building were considered.
Салах, Шеріф Фавзі
core  

The interaction of lean and building information modeling in construction [PDF]

, 2010
Lean construction and Building Information Modeling are quite different initiatives, but both are having profound impacts on the construction industry. A rigorous analysis of the myriad specific interactions between them indicates that a synergy exists ...
Bhargav A. Dave, Dehlin S., Deming W. E., Eckblad S., Forgues D., Hopp W. J., Howard R., Khanzode A., Khanzode A., Koskela L., Koskela L., Lauri Koskela, Liker J. E., Liston K., Manning R., Rafael Sacks, Rivard H., Robert Owen, Schonberger R. J., Shewhart W. A., Sriprasert E., Stevens R., Whyte J., Womack J. P.   +23 more
core   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Investigation of the Influence Mechanism and Analysis of Engineering Application of the Solar PVT Heat Pump Cogeneration System

Energies
Amidst the ongoing global energy crisis, environmental deterioration, and the exacerbation of climate change, the development of renewable energy, particularly solar energy, has become a central topic in the global energy transition.
Yujia Wu, Zihua Li, Yixian Zhang, Gang Chen, Gang Zhang, Xiaolan Wang, Xuanyue Zhang, Zhiyan Li   +7 more
doaj   +1 more source

Analysis of timber as sustainable material for construction [PDF]

, 2014
Comunicació presentada a IN-TECH 2014 International Conference on Innovative Technologies (Leiria, Portugal 10-13, september 2014).Facing the climate change scenario, professionals and technicians of civil engineering and architecture are searching for ...
Braulio-Gonzalo, Marta, Gallego Navarro, Teresa, Lecha Sangüesa, Antonio   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source