Results 121 to 130 of about 1,522,294 (308)

Preservation of panorama mesdag, the Haque [PDF]

open access: yes, 2012
This paper deals with the preservation of the Panorama Mesdag, a cylindrical painting, more than 14 meters high and 120 meters in circumference. The vista of the sea, the dunes and Scheveningen village was painted by one of the most famous painters of ...
Koning, M. de, Stoel, A.E.C. van der
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

RC Medium-Rise Building Damage Sensitivity with SSI Effect. [PDF]

open access: yesMaterials (Basel), 2022
Gaile L, Ratnika L, Pakrastins L.
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Simulation of an 1857-like Mw 7.9 San Andreas Fault Earthquake and the Response of Tall Steel Moment Frame Buildings in Southern California – A Prototype Study [PDF]

open access: yes, 2008
In 1857, an earthquake of magnitude 7.9 occurred on the San Andreas fault, starting at Parkfield and rupturing in a southeasterly direction for more than 360 km.
Beck, J. L.   +6 more
core  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

New Zealand contributions to the global earthquake model’s earthquake consequences database (GEMECD) [PDF]

open access: yes, 2015
The Global Earthquake Model’s (GEM) Earthquake Consequences Database (GEMECD) aims to develop, for the first time, a standardised framework for collecting and collating geocoded consequence data induced by primary and secondary seismic hazards to ...
Bocchini, G.   +5 more
core  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Integrating Peak Ground Acceleration as a Damage Factor in Risk-Based Premium Rate Assessment using K-medoids Bayesian networks

open access: yesJournal of Applied Science and Engineering
In the insurance market, determining fair and acceptable premium rates requires an accurate evaluation of risk. In the context of earthquake damage, the Peak Ground Acceleration (PGA) level is essential for assessing the intensity of ground shaking and ...
Devni Prima Sari   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy