Results 181 to 190 of about 1,597,081 (316)

Building Data Triangulation Capacity for Routine Immunization and Vaccine Preventable Disease Surveillance Programs to Identify Immunization Coverage Inequities. [PDF]

Vaccines (Basel)
Rachlin A, Adegoke OJ, Bohara R, Rwagasore E, Sibomana H, Kabeja A, Itanga I, Rwunganira S, Mafende Mario B, Rosette NM, Usman Obansa R, Abah AU, Adeoye OB, Sikare E, Lam E, Murrill CS, Montesanti Porter A.   +16 more
europepmc   +1 more source

Optimizing the total energy consumption and CO2 emissions by distributing computational workload among worldwide dispersed data centers

, 2015
Major internet service providers have built and are currently building the world's largest data centres (DCs), which has already resulted in significant global energy consumption.
Van Schie, Frank T., Zavřel, Vojtěch, Torrens, J. Ignacio, Garg, Vishal, Hundertmark, T. F.W., Mathur, Jyotirmay, Hensen, Jan L.M.   +6 more
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

From LIDAR Point Clouds to 3D Building Models

, 2009
High quality and dense sampling are two major properties of recent airborne LIDAR data which are still improving. In this thesis a novel approach for generating 3D building models from LIDAR data is presented. It consists of four major parts: filtering
Arefi, Hossein
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Building Monitoring System and Preliminary Results for a Retrofitted Office Building

, 2012
Existing commercial buildings in the United States consumed 18.42 quadrillion Btus of primary energy in 2008 which amounts to 18.4% of all energy consumed and 78% of all electricity in the United States (DOE 2011). The U.S.
Sweetser, Rich, Wagner, Tim, Henderson, Hugh, Dasgupta, Arindam   +3 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Detailed operational building data for six office rooms in Denmark: Occupancy, indoor environment, heating, ventilation, lighting and room control monitoring with sub-hourly temporal resolution. [PDF]

Data Brief
Melgaard SP, Johra H, Nyborg VØ, Marszal-Pomianowska A, Jensen RL, Kantas C, Larsen OK, Hu Y, Frandsen KM, Larsen TS, Svidt K, Andersen KH, Leiria D, Schaffer M, Frandsen M, Veit M, Ussing LF, Lindhard SM, Pomianowski MZ, Rohde L, Hansen AR, Heiselberg PK.   +21 more
europepmc   +1 more source

Model Transformation from SimModel to Modelica for Building Energy Performance Simulation

, 2019
BauSIM2014: 5th German-Austrian Conference of the International Building Performance Simulation Association, Aachen University, Germany, 22-24 September 2014This paper demonstrates a model transformation tool between the Building Information Model (BIM ...
O'Donnell, James, Maile, Tobias, Cao, Jun, et al., O\u27Donnell, James   +4 more
core