Results 41 to 50 of about 3,396,116 (292)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Construction Aspects of Hybrid Water-Filled Building Envelopes

Journal of Facade Design and Engineering, 2020
Water-filled building envelopes are hybrid constructions with a solid and a fluid component, typically a glass or steel shell filled with water.
Matyas Gutai, Lee Shwu-Ting, Bumpei Magori, Yu Morishita, Abolfazl Ganji Kheybari, Joshua Spencer   +5 more
doaj   +1 more source

Climate data for hygrothermal simulations of Brussels

Data in Brief, 2022
Moisture is a dominant agent in the degradation of building components. To assess degradation phenomena in building envelopes, hygrothermal simulations are performed.
Isabeau Vandemeulebroucke, Steven Caluwaerts, Nathan Van Den Bossche   +2 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Inter-Building Effect and Its Relation with Highly Reflective Envelopes on Building Energy Use: Case Study for Cities of Japan

Atmosphere, 2017
The built environment with respect to building envelope designs and the surrounding micro-environment significantly affects building energy use. The influence of the inter-building effect (IBE) on building energy use cannot be ignored and thermal ...
Jihui Yuan, Craig Farnham, Kazuo Emura
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Experimental and numerical assessment of breathing walls performance for theimprovement of air quality and comfort indoors

Tema, 2016
The construction of airtight building envelopes within nearly Zero Energy Buildings is likely to generate thermo-hygrometric discomfort indoors, that needs to be managed with airconditioning and ventilation systems.
Elisa Di Giuseppe, Marco D’Orazio
doaj   +1 more source

Improving the Thermal Performance of Building Envelopes: An Approach to Enhancing the Building Energy Efficiency Code

, 2022
Cities on the east Mediterranean coast, especially in Palestine, are struggling to move towards sustainability as they are vulnerable to climate change and lack natural resources, especially energy resources, and this situation is further aggravated by ...
Muhannad Haj Hussein, Aiman Albatayneh, Adel Juaidi, Sameh Monna, Ramez Abdallah   +4 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Sensing Envelopes: Urban Envelopes in the Smart City Ontology Framework

ISPRS International Journal of Geo-Information
The paper examines the phenomenon of urban envelopes, a conceptual parallel to building envelopes, which is considered an emerging theme in studies of the built environment.
Andrej Žižek, Peter Šenk, Kaja Pogačar   +2 more
doaj   +1 more source