Results 141 to 150 of about 4,562,946 (276)

Enhancing Building Energy Efficiency through Building Information Modeling (BIM) and Building Energy Modeling (BEM) Integration: A Systematic Review

Buildings
With the ever-increasing population and historic highest energy demand, the energy efficiency of buildings is becoming crucial. Architectural firms are moving from traditional Computer-Aided Design (CAD) to BIM.
Mohammed Alhammad, Matt Eames, Raffaele Vinai   +2 more
doaj   +1 more source

A Design for Safety (DFS) Framework for Automated Inspection Risks in Metro Stations by Integrating a Knowledge Base and Building Information Modeling. [PDF]

Int J Environ Res Public Health, 2023
Liu P, Shang Y, Zhang L.
europepmc   +1 more source

The building information modeling for the retrofitting of existing buildings. A case study in the University of Cagliari. [PDF]

, 2018
Italy's very consistent buildings stock has become the major field for real estate investments and for the related projects and actions. The urge of working on built environment is however facing some crucial issues.
Chiara Tagliabue, Lavinia, Desogus, Giuseppe, Martino Di Giuda, Giuseppe, Monni, Giuseppina, Quaquero, Emanuela, Sanna, Antonello, Villa, Valentina   +6 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Enhancing Interoperability Between Building Information Modeling and Building Energy Modeling: Alphanumerical Information Exchange for Energy Optimization in Early Design Stages

Applied Sciences
Building information modeling (BIM) has revolutionized integrated planning by optimizing costs, schedule, and material use. However, building energy modeling (BEM) remains underutilized in early design stages due to interoperability challenges between ...
Josef Miller, Larissa Schneiderbauer, Martin Hauer, Alexandra Jäger, Georg Fröch, Rainer Pfluger, Stephan Moser   +6 more
doaj   +1 more source

Building information modeling: next steps for tensile membrane architecture [PDF]

, 2015
With technologicaladvancementsin building design,increasing BIM maturity provides significantopportunities to improve the design process and performance of tensile membrane architecture.In order to isolate the next stepsof technological development for ...
Lin, Eve S.
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

BIM-Based Machine Learning Application for Parametric Assessment of Building Energy Performance

Energies
The energy performance of buildings has become a main concern globally in response to increased energy demand, the environmental impacts of energy production, and the reality of energy poverty.
Panagiotis Tsikas, Athanasios Chassiakos, Vasileios Papadimitropoulos, Antonios Papamanolis   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source