Results 121 to 130 of about 20,102,698 (277)

Design error reduction: Toward the effective utilization of building information modeling

, 2011
An advocated panacea for reducing design errors and rework in construction and engineering projects is building information modeling (BIM). Yet, it would appear that advocates of BIM have overlooked why and how design errors occur.
Han S., Sangwon Han, Love, Peter, David J. Edwards, Edwards D.J., Goh, Y.M., Han, S., Love P.E.D., Love, P.E.D., Edwards, D.J., Peter E. D. Love, Goh, Yang Miang, Yang M. Goh, Edwards, D., Goh Y.M.   +14 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Building-Information-Modeling Based Approach to Simulate Strategic Location of Shelter in Place and Its Strengthening Method. [PDF]

Materials (Basel), 2021
Kim YH, Choi JS, Yuan TF, Yoon YS.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Defining Characteristics of National BIM Adoption

ARO-The Scientific Journal of Koya University
Building information modeling (BIM) has become a transformative force in the Architecture, Engineering, and Construction industry, streamlining project coordination, reducing costs, and promoting sustainability.
Dilan M. Rostam, Dawood S Atrushi, Dawa A. A. Masih, Diman N. Abdulqader   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Other title: Kansas State Office Building Commission biennial report, July 1, 1956 to June 30, 1958

, 1958
"December 29, 1958."State Office Building Commission Members -- Letter of Transmittal -- Explanatory Foreword -- Activities During the Biennium -- Recommended Legislation -- Statement of Receipts and Disbursements -- Balance Sheet -- Operation Expenses ...
Kansas. State Office Building Commission.
core  

Effects of the Interactions Between LPS and BIM on Workflow in Two Building Design Projects [PDF]

, 2014
Variability in design workflow causes delays and undermines the performance of building projects. As lean processes, the Last Planner System (LPS) and Building Information Modeling (BIM) can improve workflow in building projects through features that ...
Khan, Sheriz, Tzortzopoulos, Patricia
core   +1 more source

Reflections on Three Decades of Building Information Modeling

Buildings
In 1994, the first European Conference on Product and Process Modelling took place in Dresden, Germany. The entire field of construction information technology research has enthusiastically embraced building information modeling (BIM) as a method for ...
Žiga Turk
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source