Results 101 to 110 of about 22,306,018 (281)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Monetizing Environmental Impacts into Environmental Costs During Prefabricated Building Construction: A 5D BIM-Enabled Analysis

open access: yesCivilEng
Although prefabricated buildings offer environmental advantages, their construction process inevitably generates environmental impacts. However, current research on prefabricated buildings focuses on the environmental impact level, and there is a lack of
Xian Gao   +3 more
doaj   +1 more source

The Role of Building Information Modeling in the Management and Operation of Existing Buildings [PDF]

open access: yesInternational Journal of BIM and Engineering Science
This research aims to highlight the importance of Building Information Modeling (BIM) in improving the management and operation of existing buildings.
Heba Eid, Alaa Kadi, Hadi Kherbeic
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Post-pandemic building resilience: Building Information Modeling and green building integration

open access: yesJournal of Civil Engineering and Management
This research explores how Building Information Modeling (BIM), green building design, and post-pandemic resilience contribute to sustainable, healthy buildings.
Masood Karamoozian, Hong Zhang
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Constructing Dispute Scenarios in Building Information Modeling

open access: yes, 2016
Somehow, disputes are inevitable in the construction industry. Rather than being carried away by the psychological nuances that are associated with relational strains in disputes, construction literature contains a wealth of knowledge on how to make the ...
Olatunji, Oluwole Alfred
core  

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