CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Retracted: Value Proposition for Enabling Construction Project Innovation by Applying Building Information Modeling. [PDF]
Intelligence And Neuroscience C.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Feature Consistent Point Cloud Registration in Building Information Modeling. [PDF]
Jiang H +4 more
europepmc +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Potential features of building information modeling (BIM) for application of project management knowledge areas in the construction industry. [PDF]
Raza MS +3 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Acceptance Model for Mobile Building Information Modeling (BIM)
Mobile Building Information Modeling (BIM) is noted for tools that enable the systematic interchange of information and contribute to enhancing collaborative performance through BIM.
Sim-Hee Hong +3 more
doaj +1 more source
Building Information Modeling Learning Behavior of AEC Undergraduate Students in China. [PDF]
Peng P +6 more
europepmc +1 more source
Design error reduction: Toward the effective utilization of building information modeling
An advocated panacea for reducing design errors and rework in construction and engineering projects is building information modeling (BIM). Yet, it would appear that advocates of BIM have overlooked why and how design errors occur.
Han S. +14 more
core +1 more source

