Results 71 to 80 of about 20,102,698 (277)
Constructing Dispute Scenarios in Building Information Modeling
Somehow, disputes are inevitable in the construction industry. Rather than being carried away by the psychological nuances that are associated with relational strains in disputes, construction literature contains a wealth of knowledge on how to make the ...
Olatunji, Oluwole Alfred
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Energy consumption in buildings depends on several physical factors, including its physical characteristics, various building services systems/appliances used, and the outdoor environment.
Uddin, MN +7 more
core +1 more source
Lean construction, building information modelling and sustainability [PDF]
This paper investigates the mutual relations of three current drivers of construction: lean construction, building information modelling and sustainability.
Owen, Bob, Koskela, Lauri, Dave, Bhargav
core +3 more sources
Enriching Building Information Modeling Models through Information Delivery Specification
The efficient acquisition and dissemination of information are crucial in building information modeling (BIM). Current BIM models face significant challenges, including inadequate modeling techniques, poorly defined information requirements, and low ...
Giancarlo de Marco +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Building information modelling: protocols for collaborative design processes [PDF]
Numerous frameworks and protocols are being developed to facilitate BIM understanding and implementation. A BIM framework is a structured theoretical construct that can assist in organizing BIM domains of knowledge and facilitate the creation of new ...
Kelly, Graham +5 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source

