Results 71 to 80 of about 1,400,684 (280)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

A Simulation Model for Logical and Operative Clash Detection [PDF]

open access: yes, 2017
The introduction of the Building Information Modeling (BIM) approach has facilitated the management process of documents produced by different kinds of professionals involved in the design and/or renovation of a building, through identification and ...
Coraglia, UGO MARIA   +5 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The role of primitive part modelling within an integrative simulation environment [PDF]

open access: yes, 2003
The component-based modeling approach to the simulation of HVAC systems has been in used for many years. The approach not only supports plant simulation but also allows the integration of the building and plant domains.
Chow, T.T., Clarke, J.A., Song, C.L.
core  

A novel representation of energy and signal transformation in measurement systems [PDF]

open access: yes, 2005
This work presents a novel representation of energy and signal transformation in a measurement system, which is essentially a transducer conversion logic or language (TCL).
Yang, QP
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Enriching Building Information Modeling Models through Information Delivery Specification

open access: yesBuildings
The efficient acquisition and dissemination of information are crucial in building information modeling (BIM). Current BIM models face significant challenges, including inadequate modeling techniques, poorly defined information requirements, and low ...
Giancarlo de Marco   +2 more
doaj   +1 more source

Teaching Stats for Data Science [PDF]

open access: yes, 2017
“Data science” is a useful catchword for methods and concepts original to the field of statistics, but typically being applied to large, multivariate, observational records.
Kaplan, Daniel
core   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Virtual Reality of Earthquake Ground Motions for Emergency Response [PDF]

open access: yes, 2017
Ground motions interface earthquake science and engineering to advance understanding of seismic hazards and risk. Virtual reality provides an attractive tool to extend knowledge of the research community to a larger audience.
Lin, Ting
core   +2 more sources

Home - About - Disclaimer - Privacy