Results 51 to 60 of about 241,946 (291)

Features and Conditions of Building Information Modeling Contracts

open access: yesBuildings, 2022
Building information modeling (BIM) has improved efficiency in construction projects by utilizing digital instrument capabilities. However, the use of this technology has brought new challenges, particularly legal and contract issues.
Siamak Nilchian   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Collaborative Factory Layout Planning With Building Information Modeling

open access: yesProceedings of the Conference on Production Systems and Logistics, 2021
Manufacturing companies are facing an increasingly turbulent environment. In order to respond to these dynamic market conditions, products and thus also production systems have to be adapted more frequently and much faster. However, time and cost targets
Neuhäuser, Thomas   +8 more
doaj   +1 more source

Influence of Occupant Behavior for Building Energy Conservation: A Systematic Review Study of Diverse Modeling and Simulation Approach

open access: yes, 2021
Energy consumption in buildings depends on several physical factors, including its physical characteristics, various building services systems/appliances used, and the outdoor environment.
Uddin, MN   +7 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Seismic retrofitting of buildings using Building Information Modeling

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2021
Building Information Modeling (BIM), in the last couple of decades, has emerged as a technology that can be used in combination with different methodologies in the fields of architecture, engineering, and construction industry as a digital model to ...
Lami S. Dereje   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An Integrated BIM-Based Application for Automating the Conceptual Design for Vietnamese Vernacular Architecture: Using Revit and Dynamo

open access: yesApplied Sciences
Vietnamese vernacular architecture (VVA), rich in cultural and historical significance, is increasingly endangered by modernization, the consequences of war, and environmental degradation.
Thai Bao Tran   +5 more
doaj   +1 more source

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