Results 81 to 90 of about 22,306,018 (281)
Science, Technologie, DéveloppementCette étude examine le rôle du Historic Building Information Modeling (HBIM) dans la préservation des barrages coloniaux et post-coloniaux, en soulignant son potentiel pour la conservation et la gestion.
David Kisalu Nzundu, David Mwila Bwalya
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Object Modeling and Building Information Modeling [PDF]
, 2016 The main part of this thesis is an online course (Small Private Online Course) entitled "Introduction to Object Modeling and Building Information Modeling".
Auråen, Hege, Gjemdal, Hanne
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Brief Introduction to Building Information Modeling (BIM) and its interoperability with TRNSYS
Renewable Energy and Sustainable Development, 2015 :Hand-drafted print, sketching and hand modeling were the standard for building designs before the advent of computer aided design (CAD) systems . Nowadays CAD systems are better understood, their adoption increased until the 2D, 3D CAD system and the ...
Abdelaziz Naamane, AbdelAziz Boukara
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Using GIS in Sustainable Urban Planning: Evaluation of Educational Services in Basilia City [PDF]
International Journal of BIM and Engineering ScienceThe study presents an applied model of how GIS technology can be used to analyze spatial information and highlight the spatial relationships between them.
Mohammad Ibrahim +2 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Building Information Modeling and Quantity Surveying Practice
, 2010 The construction industry is widely acknowledged as unique and conservative. Building Information Modeling (BIM) systems have the potential to revolutionize current practices and to automate the measurement of quantities from construction drawings ...
Sher, W., Olatunji, O. A., Gu, N.
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