Results 111 to 120 of about 241,946 (291)

Building Information Modeling in Commercial Construction Projects

, 2016
This paper explains the scope of Building information modeling in commercial construction projects, various studies performed by different researchers, background of building information modeling, data requirement and its flow between different parties ...
, Ganesh Nandkumar Gore, Prof. Abhijit. N. Bhirud
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Um jogo de tabuleiro para o processo de ensino-aprendizagem de projeto colaborativo em building information modeling

Oculum Ensaios, 2023
A obrigatoriedade do Building Information Modeling no Brasil teve início em 2021, quando entrou em vigor a primeira meta da Estratégia Building Information Modeling Brasil, onde toda obra pública do Governo Federal deve ter seu projeto apresentado em ...
Roberto Cavalleiro de Macedo Alves, Alice Theresinha Cybis Pereira   +1 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Enhancing Interoperability Between Building Information Modeling and Building Energy Modeling: Alphanumerical Information Exchange for Energy Optimization in Early Design Stages

Applied Sciences
Building information modeling (BIM) has revolutionized integrated planning by optimizing costs, schedule, and material use. However, building energy modeling (BEM) remains underutilized in early design stages due to interoperability challenges between ...
Josef Miller, Larissa Schneiderbauer, Martin Hauer, Alexandra Jäger, Georg Fröch, Rainer Pfluger, Stephan Moser   +6 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

BIM-Based Machine Learning Application for Parametric Assessment of Building Energy Performance

Energies
The energy performance of buildings has become a main concern globally in response to increased energy demand, the environmental impacts of energy production, and the reality of energy poverty.
Panagiotis Tsikas, Athanasios Chassiakos, Vasileios Papadimitropoulos, Antonios Papamanolis   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Integrating Building Management Systems in High-Rise Structures using Building Information Modeling

Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUA
Rapid industrialization and population growth in urban areas has resulted in scarce land resources thus changing built form tremendously. Complex construction such as high-rise structures are becoming an essential requirement in urban areas.
Purva Mujumdar, Shlok Agarwal
doaj   +1 more source

Building-Information-Modeling Based Approach to Simulate Strategic Location of Shelter in Place and Its Strengthening Method. [PDF]

Materials (Basel), 2021
Kim YH, Choi JS, Yuan TF, Yoon YS.
europepmc   +1 more source