T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Does size matter? Experiences and perspectives of BIM implementation from large and SME construction contractors [PDF]
This paper presents the findings of a qualitative study into the experiences and perspectives of large and SME construction contractors towards the implementation of Building Information Modelling (BIM) within their organisations.
Bleanch, Paula +2 more
core
How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges?
This review examines how artificial intelligence reshapes sustainable building design faced with climate change challenges. The authors synthesize existing studies to demonstrate AI's transformative potential across design lifecycle phases from climate‐aware form generation to performance optimization.
Pengyuan Shen +5 more
wiley +1 more source
Addressing the limitations of current digital simulations for historical buildings, this paper suggests a specific technical task for the development of a simulation analysis platform based on City Intelligent Modelling (CIM).
Dmytro Chashyn +2 more
doaj +1 more source
Structural Analysis Ready Building Information Modelling: A Requirement Analysis [PDF]
Structural analysis is utilised to evaluate the behaviour of structures under applied loads to ensure their safety and stability. It is crucial in designing, assessing, and retrofitting buildings and structures.
M. Akhoundi Khezrabad +2 more
doaj +1 more source
Historic Building Information Modelling (BIM) According to BIM ISO
Rumah kampung, or Malay house, exemplifies the richness and insight of traditional buildings, sharing a home with people, and living in peace with nature. The typical Malay home is a building elevated on stilts high above the ground, covered with thatch roofs, encased with wooden walls, and pierced with windows and lattices in its most basic form.
Siti Azira Abd Rahim +6 more
openaire +1 more source
Architectural Information Modelling for Virtual Heritage Application [PDF]
In today’s AEC industry (Architecture, Engineering and Construction industry), there has been a vast evolution in the usage of information and communication technology (ICT) for describing and managing construction projects.
De Meyer, RonaldTW018010007763600000-0002-3915-765XF47FBAF0-F0ED-11E1-A9DE-61C894A0A6B4 +4 more
core +1 more source
Abstract Blockchain technology is a digital decentralized data ledger recording transactions in an encrypted format. Its implementation can potentially hold significant advantages for the built environment, particularly in manufacturing and building product usage aligned with Building Information Modeling (BIM). This paradigm shift toward decentralized
Aileen Pfeil +2 more
wiley +1 more source
Comparative analysis of technologies and methods for automatic construction of building information models for existing buildings [PDF]
Building Information Modelling (BIM) provides an intelligent and parametric digital platform to support activities throughout the life-cycle of a building and has been used for new building construction projects nowadays. However, most existing buildings
Lee, SH, Lu, Q
core
Comparative study on the perspective towards the benefits and hindrances of implementing building information modelling (BIM) [PDF]
Building Information Modelling (BIM) is considered one of the most effective technologies to improve the productivity of the building process. BIM has proven its advantages throughout the building project life cycle.
Al-Ashmori, Yasser Yahya +2 more
core +2 more sources

