T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Does size matter? Experiences and perspectives of BIM implementation from large and SME construction contractors [PDF]
This paper presents the findings of a qualitative study into the experiences and perspectives of large and SME construction contractors towards the implementation of Building Information Modelling (BIM) within their organisations.
Bleanch, Paula +2 more
core
Extraction of main levels of a building from a large point cloud [PDF]
Horizontal levels are references entities, the base of man-made environments. Their creation is the first step for various applications including the BIM (Building Information Modelling).
Ferrarese, Stefano +3 more
core +1 more source
2D Metal‐Organic Frameworks for High‐Performance Solid‐State Electrolytes: A Comprehensive Review
In this review, we elucidate the intrinsic advantages, synthetic methodologies, structural characteristics, ion‐transport mechanisms and performance optimization strategies while highlighting representative material systems and applications of 2D MOFs for electrolyte applications.
Changchun Ai +8 more
wiley +1 more source
Addressing the limitations of current digital simulations for historical buildings, this paper suggests a specific technical task for the development of a simulation analysis platform based on City Intelligent Modelling (CIM).
Dmytro Chashyn +2 more
doaj +1 more source
Structural Analysis Ready Building Information Modelling: A Requirement Analysis [PDF]
Structural analysis is utilised to evaluate the behaviour of structures under applied loads to ensure their safety and stability. It is crucial in designing, assessing, and retrofitting buildings and structures.
M. Akhoundi Khezrabad +2 more
doaj +1 more source
Architectural Information Modelling for Virtual Heritage Application [PDF]
In today’s AEC industry (Architecture, Engineering and Construction industry), there has been a vast evolution in the usage of information and communication technology (ICT) for describing and managing construction projects.
De Meyer, RonaldTW018010007763600000-0002-3915-765XF47FBAF0-F0ED-11E1-A9DE-61C894A0A6B4 +4 more
core +1 more source
Historic Building Information Modelling (BIM) According to BIM ISO
Rumah kampung, or Malay house, exemplifies the richness and insight of traditional buildings, sharing a home with people, and living in peace with nature. The typical Malay home is a building elevated on stilts high above the ground, covered with thatch roofs, encased with wooden walls, and pierced with windows and lattices in its most basic form.
Siti Azira Abd Rahim +6 more
openaire +1 more source
ABSTRACT Our planet faces a critical crisis, with pollution, resource depletion and biodiversity loss surpassing sustainable limits. Businesses must address these challenges, with the circular economy and Industry 4.0 offering transformative potential through closed‐loop systems, regenerative solutions and advanced technologies.
Agnes Toth‐Peter +3 more
wiley +1 more source
Comparative analysis of technologies and methods for automatic construction of building information models for existing buildings [PDF]
Building Information Modelling (BIM) provides an intelligent and parametric digital platform to support activities throughout the life-cycle of a building and has been used for new building construction projects nowadays. However, most existing buildings
Lee, SH, Lu, Q
core

