Results 91 to 100 of about 261,938 (308)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Rule-based integrated building management systems

open access: yes, 1993
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The introduction of building management systems in large buildings have improved the control of building services and provided energy savings.
Clark, Gary George, Clark, G.G
core  

The efficiency and effectiveness of building maintenance for College Tun Hussein Onn (KTHO), Universiti Teknologi Malaysia [PDF]

open access: yes, 2010
Buildings are the most valuable assets in a nation, which providing people with shelter and facilities for work and leisure. A correspondingly strong building conservation movement has also directed attention towards the older built stock such as the ...
Wong, Chin Liang
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Maintenance, building depreciation and land rent [PDF]

open access: yes, 2013
This paper aims to explore three closely related issues: building maintenance, building depreciation, land rent. What makes these three issues deeply connected is the market value of the property.
MANGANELLI, BENEDETTO
core   +1 more source

Endurance of the wooden bridge reinforced by the dowel plates

open access: yesStudia Geotechnica et Mechanica, 2018
The most important piece of road infrastructure is bridges. Wooden bridges have advanced constantly during the past decades. The trend began in Scandinavian countries but has also now gained significant ground in Russia.
Dahoua Lamri, Boymatov Fakhridine
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Role of Maintenance and Facility Management in Logistics: A Literature Review [PDF]

open access: yes, 2014
Purpose - The purpose of this paper is to provide a literature review on the different ways of carrying out Facility Management and related topics in order to uncover that there is limited research regarding the impact of Facility Management on the ...
De Marco, Alberto, Mangano, Giulio
core   +1 more source

Maintenance Building: Frame construction

open access: yes, 2020
The black and white photographs document the early development of the ...
Commonwealth News and Information Bureau   +1 more
core   +1 more source

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