Results 121 to 130 of about 1,677,818 (304)
Group Maintenance Behaviors in the Decision-Making Styles of Self-Organizing Distributed Teams [PDF]
Businesses, universities, and other organizations are increasingly reliant on self-organizing, distributed teams which are enabled by information and communication technologies (ICTs).
Crowston, Kevin +3 more
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
DESIGN SPESIAL MAINTENANCE BANGUNAN DERAH IRIGASI IYAY RILAULAMPUNGSELATAN [PDF]
The maintenance works of inigation network are needed to maintain irrigation infrastructure to be well functioned and operable. The building shall be defected due to natural causes which would make the dimension to become nonstandard, hence the effort ...
Besperi, Besperi
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Maintainability factors for robust maintainance integrated design (R-MInD) in building design [PDF]
Building maintainability considerations relate to the extent to which the building maintenance tasks could be seen as being achievable. The purposes of incorporating good maintainability considerations into building designs are to achieve high building ...
Ismail, Neza, Mohamad, Mohamad Ibrahim
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Implementation Of Life Cycle Cost in The Bus Station Building
With the increase in existing development, of course, there must be consideration of careful cost planning to support planning, use, and the end of the building service period, particularly in the building industry.
Divan Yoan Alvino Damanik
doaj +1 more source
The assessment of building defects maintenance in hospital building [PDF]
Malaysia is one of the development countries that rapidly growing in all sectors including construction sector. Hospital is one of the government sectors in Malaysia that has many assets, needs maintenance to prevent the assets from deterioration.
Nordiyana, Ab.llah
core
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source

