Results 161 to 170 of about 261,938 (308)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

The Architecture of Care: Maintenance Cycles for an Intentional Caregiving Community

open access: yes, 2018
This thesis celebrates the work of care, caregiving for a person and caretaking for a building. It argues that these two maintenance processes are worthy drivers of architectural design as they are central to the relationship of people to their built ...
Casson, Jane
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The "architectural impact" of condition monitoring equipment in design/re-adaptation of building components for preventive maintenance purposes

open access: yes, 1996
The paper examines the implications of innovative equipments-used for condition measurement in preventive monitoring purposes-over the design requirements of new buildings and in the re-adaptation criteria of existing ones.
G. NERI SERNERI, DI GIULIO, Roberto
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Building Maintenance Price Book

open access: yes, 1988
SIGLEAvailable from British Library Document Supply Centre- DSC:2361.78(8) / BLDSC - British Library Document Supply CentreGBUnited ...
Building Maintenance Cost Information Service Ltd., Kingston upon Thames (United Kingdom)
core  

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