Results 81 to 90 of about 1,677,818 (304)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Methodological Approach to Assessing Constructability in Building Maintenance and Its Impact on University Quality

Buildings
This study introduces and evaluates an innovative methodology for assessing constructability in the maintenance of university buildings, aiming to improve the quality of academic infrastructure.
Mónica Escate, Doris Esenarro
doaj   +1 more source

Study on the Construction Performance of Zeolite Asphalt Mixture Based on Macro-Micro Scale

Advances in Materials Science and Engineering, 2020
In order to explore the construction performance of zeolite asphalt mixture, the microproperties of zeolite and the macroproperties of zeolite asphalt mixture were studied.
Zhuolin Li, Junda Ren, Jianping Zhu, Wei Li, Xingsheng Fu, Liying Yang   +5 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Manajemen Pemeliharaan Fasilitas Dalam Pengelolaan Gedung [PDF]

, 2008
Maintenance frequently considered not urgently compared than construction, so the maintenance aspect is not be taken care. If the maintenance not doing, it will cause the economics value and physical value will be descending.The complex problems to ...
Labombang, M. (Mastura)
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The building information modeling for the retrofitting of existing buildings. A case study in the University of Cagliari. [PDF]

, 2018
Italy's very consistent buildings stock has become the major field for real estate investments and for the related projects and actions. The urge of working on built environment is however facing some crucial issues.
Chiara Tagliabue, Lavinia, Desogus, Giuseppe, Martino Di Giuda, Giuseppe, Monni, Giuseppina, Quaquero, Emanuela, Sanna, Antonello, Villa, Valentina   +6 more
core   +1 more source

Digital libraries and minority languages [PDF]

, 2005
Digital libraries have a pivotal role to play in the preservation and maintenance of international cultures in general and minority languages in particular.
Bainbridge, David, Dewsnip, Michael, Keegan, Te Taka Adrian Gregory, Nichols, David M., Witten, Ian H.   +4 more
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Inadequate housing in Ghana [PDF]

Urbani Izziv, 2011
Two themes are evident in housing research in Ghana. One involves the study of how to increase the number of dwellings to correct the overall housing deficit, and the other focuses on how to improve housing for slum dwellers.
Franklin Obeng-Odoom, Laurence Amedzro
doaj