Results 111 to 120 of about 3,216,643 (295)

Bond behaviour of thin concrete overlays for maintenance of concrete pavements

MATEC Web of Conferences, 2018
Concrete pavements are exposed to a number of stresses during their service life, mostly resulting from traffic and climate conditions. In consideration of the continuously rising traffic volume, the durability requirements of concrete pavements become ...
Breitenbücher Rolf, Schulte-Schrepping Christoph, Kunz Sebastian   +2 more
doaj   +1 more source

DESIGN TOOLS FOR LIFE CYCLE ANALYSIS AND DURABILITY EVALUATION OF BUILDING SYSTEMS: A RESEARCH ON THE BUILDING ENVELOPE [PDF]

, 2013
The behavior and service life prediction of building systems requires to develop tools to assist the designer. The paper is focused on a research carried out in the Department of Architecture and Design with the Department of Mathematical Sciences of the
Levra Levron, Andrea, Pellerey, Franco, Pollo, Riccardo   +2 more
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Seismographic recording of large rocket engine operation [PDF]

, 1969
Recording equipment for rocket engine vibration is adaptable to determining the structural strength of building materials. This seismographic system is portable and is capable of measuring displacements in the direction of three mutually perpendicular ...
Dalins, I., Mc Carty, V.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Heritage ++, a Spatial Computing approach to Heritage Conservation

RILEM Technical Letters
Historic structures are affected by numerous degradation processes driven by a complex system of interconnected and mutually influencing factors. Preserving these monuments is a multidisciplinary endeavour that extends beyond one-time interventions ...
Yamini Patankar , Camilla Tennenini, Rafael Bischof, Ishita Khatri, Ricardo Maia Avelino, Wenqian Yang, Nijat Mahamaliyev, Fabio Scotto, Daniela Mitterberger, Bernd Bickel, Fred Girardet, Christophe Amsler, Brahimsamba Bomou, Robert J. Flatt   +13 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Quantifying structural distortion manipulation for desired perovskite phase: Part I. Paradigm demonstration in tungsten oxides

Journal of Materiomics
Slight distortions can cause dramatic changes in the properties of crystalline perovskite materials and their derivatives. Due to the numerous types of distortions and unclarified distortion-structure relations, a quantitative distortion manipulation for
Cheng Fang, Hong Wang, Siqi Shi
doaj   +1 more source

Digital wood craft [PDF]

, 2009
In 1995, Robin Evans points out in his book The Projective Cast how the development of techniques changed architecture and the space inhabited in times of Gothic and early Renaissance. We see a parallel phenomenon today, where the interplay of technology
Ramsgaard Thomsen, Mette, Tamke, Martin
core