Results 71 to 80 of about 1,174,972 (306)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Facing the growing problem of the electric power consumption in Egyptian residential building using building performance simulation program [PDF]

, 2013
Egypt has been experiencing recurrent power cuts especially at the summer, with the problem being made worse by the extra demands placed on the electrical grid by the advent of the holy month of Ramadan.
Elharidi, Aly Mohamed Aly Hassan, Teamah, M., Tuohy, Paul Gerard   +2 more
core  

Analysis of a residential building energy consumption as “base model” in Tripoli, Lebanon [PDF]

, 2016
The interest in energy performance of buildings in Lebanon has increased in the last few years. Indeed, many organizations are evaluating the commercial buildings’ energy performance in order to increase the commercial sector energy efficiency.
Yathreb, S.
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Towards an overheating risk tool for building design [PDF]

, 2013
PurposeThe work set out to design and develop an overheating risk tool using the UKCP09 climate projections that is compatible with building performance simulation software.
Banfill, Phillip Frank Gower, Gibson, Gavin Jarvis, Gul, Mehreen, Jenkins, David, Menzies, Gillian Frances, Patidar, Sandhya   +5 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Dromedary Camel: A Biomimetic Approach for Improving Energy Efficiency in Desert Buildings: A Case Study in Sinai [PDF]

SINAI International Scientific Journal
Nature inspires architects, allowing them to generate ideas and respectively handle the architectural challenges. Biomimicry serves as an empirical illustration of this inspiration in architecture.
Omnya Mohamed Zekry
doaj   +1 more source

A new thermal analysis by numerical simulation to investigate the energy performance of buildings [PDF]

, 2011
12th Conference of International Building Performance Simulation ...
Ballarini, Ilaria, Corrado, Vincenzo
core  

History and development of validation with the ESP-r simulation program [PDF]

, 2008
It is well recognised that validation of dynamic building simulation programs is a long-term complex task. There have been many large national and international efforts that have led to a well-established validation methodology comprising analytical ...
Ben-Nakhi, Bloomfield, G. Kokogiannakis, Haddad, I.A. Macdonald, P.A. Strachan, Strachan   +6 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source