Results 31 to 40 of about 6,718 (256)
Payment of Labour Wage for Construction Site Operations with Safety Risk
Management Dynamics in the Knowledge Economy, 2022 The increasing rate of unsafe acts by construction workers during construction operations to earn more wages is raising new concerns due to its negative effects; including accidents on construction sites.
Peter Uchenna OKOYE +3 more
doaj
Moneda, intercambios efectivos y desempleo keynesiano
Lecturas de Economía, 2009 El objetivo de este artículo es construir un modelo que produzca equilibrios con desempleo involuntario en una economía monetaria descentralizada. La existencia del desempleo involuntario reposa aquí sobre la organización monetaria de las transacciones ...
Ludovic Julien
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Custom v. Standardized Risk Models
Risks, 2015 We discuss when and why custom multi-factor risk models are warranted and give source code for computing some risk factors. Pension/mutual funds do not require customization but standardization.
Zura Kakushadze, Jim Kyung-Soo Liew
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Using Modularity to Reduce Complexity of Industrialized Building Systems for Mass Customization
Energies, 2017 It is widely known that industrialized building systems can positively impact construction projects in terms of efficiency, duration, safety, and quality. Although the use of industrialized building systems can potentially simplify the production process
Daniela D. Viana +2 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Moneda, intercambios efectivos y desempleo keynesiano
Lecturas de Economía, 2003 This paper aims at building up a simple model of a decentralized monetary economy with Keynesian unemployment. The existence of involuntary unemployment is based on the organization of trades.
Ludovic Julien
doaj
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source