Results 121 to 130 of about 2,125,522 (310)

Registration of Priority Rights to Building Use Rights Certificates (HGB) Registered In The Name of a Bankrupt Legal Entity

Journal of Law, Politic and Humanities
The purpose of this study is to examine the legal certainty of Priority Rights holders as outlined in Government Regulation No. 18 of 2021 concerning the Registration of Rights for holders of Building Use Rights (HGB) if the rights holder has been declared bankrupt.
Salmon Sihite, Gunawan Widjaja
openaire   +1 more source

POWER LESSONS: Women's Advocacy and the 2030 Agenda [PDF]

, 2017
In September 2015, the 193 member states of the United Nations General Assembly adopted the 2030 Agenda for Sustainable Development. Comprised of 17 Sustainable Development Goals (SDGs) and 169 related targets, the "2030 Agenda" tackles a range of global
Katherine Austin-Evelyn, Susan Y. Wood
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

From motherhood to maternal subjectivity [PDF]

, 2001
In this paper I try to work out what would be involved - and what would be some of the implications - in moving from the idea of motherhood to maternal subjectivity (which I theorise through the lens of unconscious intersubjectivity). Motherhood connotes
Hollway, Wendy
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Issues Affecting Women Programme's New Strategy and Strategic Learning and Evaluation System [PDF]

, 2012
The Issues Affecting Women Programme (IAWP) developed a new strategic plan over the course of 2011 with two pillars: building women's rights movements and combating violence against women. These pillars branch out into four core Programme Areas: movement

core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Making Women's Voices Count in Community Decision-Making on Land Investments [PDF]

, 2016
The adverse impacts of commercialization and largescale land acquisitions in the global South are often disproportionately borne by women. The loss of access to farmland and common areas hit women harder than men in many communities, and women are often ...
CELINE SALCEDO-LA VIÑA, MAITRI MORARJI
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source