Results 81 to 90 of about 2,125,522 (310)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Collaborative mapping of water conflicts in Andalusia, Spain [PDF]

, 2017
This project builds on previous studies, to construct a process of social and collaborative mapping that leads to the production of a map on water conflicts in Andalusia (Spain).
Cabello Villarejo, Violeta, Figueroa, Antonio, Laconi, Cesare, Mancilla Garcia, María, Moral Ituarte, Leandro del, Orozco Frutos, Gabriel, Pedregal Mateos, Belén, Romero Raposo, Juan   +7 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Freedom of Information Act Performance, 2012: Agencies Are Processing More Requests but Redacting More Often [PDF]

, 2013
A building block of American democracy is the idea that citizens have a right to information about how their government works and what it does in their name.
Gavin Baker, Sean Moulton
core  

Progressing the rights to light debate: Part 2: the grumble point revisited [PDF]

, 2005
Purpose - The paper examines the origins of the so-called "grumble point" (a sky factor of 0.2 per cent) as the measure of daylight adequacy in rights to light disputes.
Chynoweth, P
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Problems of improvement of the civil legislation on the limited real rights in the sphere of land USE

RUDN Journal of Law, 2014
In article an attempt of identification of the directions of improvement of the civil legislation on the limited real rights in the sphere of land use is made.
A S Ivanova
doaj  

Penolakan Pemberian Rekomendasi Pembebanan Hak Tanggungan Terhadap Hak Guna Bangunan di atas Hak Pengelolaan Pemerintah Kalimantan Timur

Jurnal Magister Hukum Udayana, 2018
The aim of the study was to find out the misinterpretation in the East Kalimantan Government in the gubernatorial letter number: 593/5102 / BP-II / VI / 2012 concerning the reasons for refusing to provide recommendations for the guarantee of Underwriting
Diera Ajeng Amalia
doaj   +1 more source

Independence of a Regulatory Institution - a Means to Alleviate Credibility Problems in the CEE Countries [PDF]

In Hungary and the Central-European region, state regulation has been at the forefront of interest since the beginning of the economic transition.
Gabor Virag
core  

FAKTOR PENYEBAB MENURUNNYA KEGIATAN PERUBAHAN HAK DARI HAK GUNA BANGUNAN MENJADI HAK MILIK UNTUK RUMAH TINGGAL DI KABUPATEN PATI [PDF]

, 2017
The change of right to land from the right to use the building into property rights is policy of the government implemented by BPN, namely the right to use the building increased the right to property rights for residential property.
TIMOTIUS, FEBRIANTO
core