Results 81 to 90 of about 130,724 (265)

LARANGAN PENGASINGAN TANAH DAN PELUANG INVESTASI ASING DI INDONESIA

Jurnal Media Hukum, 2014
Throughout the political history, agrarian law in Indonesia recognize the prohibition of land alienation. Foreigners or  foreign  legal  entities  (foreign  investors) were  banned  for  land  ownership.
FX Sumarja
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Automatic Construction of 3D Building Property Rights Model Based on Visual Programing Language in China

Advances in Civil Engineering
The accelerated development of society and the rapid advancement of urbanization are among the reasons for the current shortage of land resources. In China, the pressure of land resource shortage, the increasing height and complexity of buildings in ...
Guocheng Qin, Yuqing Hu, Ling Wang, Ke Liu, Yimei Hou   +4 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Human Rights Violations in Myanmar and the Military Junta’s Defensive Human Rights Diplomacy

Journal of International Studies, 2020
Once considered the internal domain of states, of late human rights issues and concerns have been frequently raised at the international level through the use of human rights diplomacy.
Jatswan S. Sidhu
doaj  

Land Holding Rights of Fulani Pastoralists and its Effect on their Agropastoral Production System in Ogun State, Nigeria [PDF]

Tropicultura, 2009
The study focuses on land holding rights of the Fulani pastoralists and its effect on their agropastoral production system. It was discovered that among the land holding rights options available for land users in Yoruba communities where the Fulanis are ...
Sodiya, CI., Adedire, MO., Lawal-Abebowale, OA.   +2 more
doaj  

Juridical Study of Ownership Rights over Apartment Units on Land with Building Use Rights for Foreign Citizens

NOTARIIL Jurnal Kenotariatan
Indonesia has great potential in the field of tourism, especially in Bali, which encourages foreign nationals (WNA) to own residences in Indonesia. However, land ownership by foreign nationals is restricted by provisions in the Basic Agrarian Law (UUPA).
Anang Muhammad Rizaldi, Ida Bagus Agung Mahesora Mas, Christian Isacc Alexander Alianto, Nur Imam   +3 more
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source