Results 121 to 130 of about 3,009,804 (314)

Improving Thermal Energy Performance of UK Built Environment through the Use of Shading Devices [PDF]

open access: gold, 2021
Bahareh Salehi   +4 more
openalex  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Knowledge management research within the built environment: Research methodological perspectives [PDF]

open access: yes
As built environment is of major importance to all societies and economies, it is essential that the discipline advances as rapidly and rigorously as possible.
Amaratunga, Dilanthi   +2 more
core  

Wave propagation over a submerged bar: benchmarking of VoF, sigma transformation, and SPH numerical models against physical wave flume tests

open access: yesDiscover Applied Sciences
Accurate prediction of wave transformation is key in the design of coastal and nearshore structures which typically depends on numerical models. Turbulent and rotational effects call for the use of Computational Fluid Dynamics (CFD) solvers of which a ...
Jacob Andersen   +3 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Dataset of smart heat and water meter data with accompanying building characteristics

open access: yesData in Brief
The data presented were sourced from 34,884 commercial smart heat meters and 10,765 commercial smart water meters, spanning a timeframe of up to 5 years (2018–2022). All data primarily originated from single-family houses in Aalborg Municipality, Denmark.
Markus Schaffer   +7 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Enhancing capacities for disaster mitigation and reconstruction in the built environment: a case study from Sri Lanka [PDF]

open access: yes
Throughout the recent decades, natural and man-made disasters have demonstrated the fragility of the built environment and its vulnerability to hazards.
Amaratunga, Dilanthi   +2 more
core  

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