Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
0.5-V Nano-Power Shadow Sinusoidal Oscillator Using Bulk-Driven Multiple-Input Operational Transconductance Amplifier. [PDF]
Sensors (Basel), 2023 Khateb F, Kumngern M, Kulej T, Yavari M.
europepmc +1 more source
Low Power Low Voltage Bulk Driven Balanced OTA
International Journal of VLSI Design & Communication Systems, 2011 International Journal of VLSI design & Communication Systems (VLSICS) Vol.2, No.4, December 2011, 131 ...
Neha Gupta +3 more
openaire +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
IMPROVING BANDWIDTH OF FLIPPED VOLTAGE FOLLOWER USING GATE-BODY DRIVEN TECHNIQUE [PDF]
Journal of Engineering Science and Technology, 2017 In this paper, a new approach to enhance the bandwidth of flipped voltage follower is explored. The proposed approach is based on gate-body driven technique.
VANDANA NIRANJAN +2 more
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Elastic properties of Zr-based bulk metallic glasses studied by resonant ultrasound spectroscopy [PDF]
We report measurements of the elastic properties of Zr-based bulk metallic glasses, Zr52.5Cu17.9Ni14.6Al10Ti5, Zr50Cu30Ni10Al10, and Zr50Cu40Al10 between 5 K and 300 K.
Zhang, Zhiying +4 more
core +1 more source
Dust emission in powder handling: Free falling particle plume characterisation [PDF]
, 2009 Dust generation during solids handling, principally from the free falling of bulk materials and their impact on stockpiles, can be a health threat for operators and a cause of dust explosions.
Ansart, Renaud +5 more
core +1 more source
Observation of current-induced bulk magnetization in elemental tellurium
Nature Communications, 2017 Electrical control of magnetic response in bulk material without electric or magnetic order is rare and potentially attractive for high efficient spintronics.
Tetsuya Furukawa +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source