Results 131 to 140 of about 1,383,288 (303)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

SOIL RESPIRATION AND BULK DENSITY UNDER ORGANIC AND CONVENTIONAL FARMING SYSTEMS

open access: yesColloquium Agrariae, 2019
The aim of this study was to evaluate, in the field, the soil respiration and bulk density under conventional and organic farming plots. The evaluations were made in different plots established as conventional farming system and organic farming system ...
Antonio Silva   +5 more
doaj  

Measured acoustic properties of variable and low density bulk absorbers [PDF]

open access: yes
Experimental data were taken to determine the acoustic absorbing properties of uniform low density and layered variable density samples using a bulk absober with a perforated plate facing to hold the material in place.
Dahl, M. D., Rice, E. J.
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Comparison of bulk snow density measurements using different methods

open access: yesAdvances in Climate Change Research
Snow density is one of the basic properties used to describe snow cover characteristics, and it is critical for remote sensing retrieval, water resources assessment and modeling inputs. There are many instruments available to measure snow density in situ.
Hang Su   +5 more
doaj   +1 more source

Analytical modelling of soil porosity and bulk density across the soil organic matter and land-use continuum. [PDF]

open access: yesSci Rep, 2022
Robinson DA   +9 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy