Results 141 to 150 of about 1,385,356 (302)

Comparison of bulk snow density measurements using different methods

open access: yesAdvances in Climate Change Research
Snow density is one of the basic properties used to describe snow cover characteristics, and it is critical for remote sensing retrieval, water resources assessment and modeling inputs. There are many instruments available to measure snow density in situ.
Hang Su   +5 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

A STUDY ON A MEASUREMENT SYSTEM FOR DETERMINING BULK DENSITY OF UNSATURATED SOILS BASED ON SOIL GAS PERMEABILITY

open access: yesEngenharia Agrícola
Soil compaction alters soil structure, reduces soil air permeability, and adversely impacts crop growth. However, the rapid field detection of soil compaction remains a significant technical challenge.
Shang Gao   +4 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Soil bulk density assessment in Europe

open access: yesAgriculture, Ecosystems & Environment
The topsoil Land Use and Cover Area frame Statistical survey (LUCAS) aims at collecting harmonised data about the state of soil health over the extent of European Union (EU). In the LUCAS 2018 survey, bulk density has been analysed for three depths, i.e., 0-10 cm = 6140 sites; 10-20 cm = 5684 sites and 20-30 cm =139 sites.
Panagos, Panos   +5 more
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Pengaruh Jenis Kemasan dan Lama Penyimpanan terhadap Serangan Serangga dan Sifat Fisik Ransum Broiler Starter Berbentuk Crumble

open access: yesJurnal Ilmiah Ilmu-Ilmu Peternakan, 2009
Storage  of  feedstuff  is  required  because  development  of  farm  must  be  made  balance  with availability of adequate feedstuff. Storage will influence physical properties of feedstuff. Packaging is the one of methods to take care product.
Yuli Retnani   +2 more
doaj  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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