Results 71 to 80 of about 1,385,356 (302)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Remote Sensing, 2015 Leaf biomass distribution is a key factor for modeling energy and carbon fluxes in forest canopies and for assessing fire behavior. We propose a new method to estimate 3D leaf bulk density distribution, based on a calibration of indices derived from T ...
François Pimont +4 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
, 2008 We present the results of a molecular dynamics simulation study of thermodynamic and structural properties upon supercooling of a low concentration sodium chloride solution in TIP4P water and the comparison with the corresponding bulk quantities.
Allen M. P. +9 more
core +1 more source
General method to retrieve all effective acoustic properties of fully-anisotropic fluid materials in three dimensional space [PDF]
, 2018 Anisotropic fluid materials are of growing interest with the development of metamaterials and transformation acoustics. In the general three-dimensional case, such materials are characterized by a bulk modulus and a full symmetric matrix of density. Here,
Cavalieri, Théo +5 more
core +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Real space first-principles derived semiempirical pseudopotentials applied to tunneling magnetoresistance [PDF]
, 2004 In this letter we present a real space density functional theory (DFT) localized basis set semi-empirical pseudopotential (SEP) approach. The method is applied to iron and magnesium oxide, where bulk SEP and local spin density approximation (LSDA) band ...
F. Aurenhammer +9 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Entanglement and Density Matrix of a Block of Spins in AKLT Model
, 2008 We study a 1-dimensional AKLT spin chain, consisting of spins $S$ in the bulk and $S/2$ at both ends. The unique ground state of this AKLT model is described by the Valence-Bond-Solid (VBS) state.
A. Affleck +68 more
core +1 more source