Results 91 to 100 of about 5,242,910 (302)

Novel surface engineering design enabled surface multifunctionalisation of metastable Ti–15–3 β-titanium alloy

Friction
The growing demand for high-performance and long-service components for challenging and resource-intensive applications has driven the development of high-strength metastable β-titanium alloys with multifunctional surfaces. In this study, a novel surface
Tong Pan, Xuan Huang, Behnam Dashtbozorg, Siyu Sun, Yepeng Yang, Ke Ren, Artemis Stamboulis, Xiaoying Li, Kan Ma, Hanshan Dong   +9 more
doaj   +1 more source

A study on Non-Markovian Bulk Arrival And Bulk Service with Multiple Vacations

International Journal of Engineering Technology and Management Sciences, 2020
A queue or a waiting line, involves arriving customers who is waiting to be served at one or more service stations, by one or more servers. The term ‘customer’ may refer, for example, to a machine arriving at an inspection center or to a person arriving at a booking counter in a railway station.
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Application of Ice Pigging in a Drinking Water Distribution System: Impacts on Pipes and Bulk Water Quality

Engineering
Ice pigging is an emerging technique for pipe cleaning in drinking water distribution systems. However, substantial confusion and controversy exist on the potential impacts of ice pigging on bulk water quality.
Yujing Huang, Zhiwei Chen, Guilin He, Yu Shao, Shuang Song, Feilong Dong, Tuqiao Zhang   +6 more
doaj   +1 more source

EFFECT OF STEEL FIBERS ON REFRACTORY CASTABLES

Journal of Engineering, 2002
Reinforcement of refractory castables with steel fibers improves their strength for cracking and spalling and expands the service life. The results show that raising the temperature from 700°C to 900°C causes an increase in porosityand decrease in ...
Abeer Abdul Kader AL-Rawi, Zain Al-Abdeen Raouf, Firas Faisal Al-Hamdani   +2 more
doaj   +1 more source

Letter to the Editor—Multichannel Queuing System with Bulk Service [PDF]

Operations Research, 1968
A multichannel queuing system with unlimited Poisson input and exponential service is considered under a bulk-service discipline. Earlier results by Arora for the two-channel case have been generalized to c (c ≥ 2) channels by using standard generating functions and Laplace transform methods.
openaire   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Integrated Transmission and Distribution Co-Simulation Platform for Demonstration of Bulk Grid Services Using Distributed Energy Resources

Energies
In September 2020, the Federal Energy Regulatory Commission (FERC) released Order 2222, which opens wholesale markets to small-capacity distributed energy resources (DERs), recognizing their potential in improving operational efficiency by providing bulk
Venkateswara Reddy Motakatla, Weijia Liu, Jun Hao, Harsha Vardhana Padullaparti, Utkarsh Kumar, Seong Lok Choi, Ismael Mendoza   +6 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source