Results 41 to 50 of about 17,747 (199)
Absence of the Klotho Function Causes Cornea Degeneration with Specific Features Resembling Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy. [PDF]
The Klotho loss-of-function mutation is known to cause accelerated senescence in many organs, but its effects on the cornea have not been published. The present study aims to investigate the effects of the Klotho null mutation on cornea degeneration and ...
Wu CY +5 more
europepmc +2 more sources
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao +10 more
wiley +1 more source
A. Bullous Keratopathy before DSAEK with a clear lens. B. Clear corneal endothelial lenticule with a clear lens 12 months after DSAEK.
Rong-mei Peng (405853) +4 more
core +1 more source
Bullous keratopathy: etiopathogenesis and treatment [PDF]
Bullous keratopathy is characterized by corneal stromal edema with epithelial or subepithelial bullae due to cell loss and endothelial decompensation.
Gonçalves, Eliana Domingues [UNIFESP] +9 more
core +1 more source
ABSTRACT Background To synthesise available evidence on the prevalence, treatment strategies, and outcomes of corneal disease affecting Aboriginal and Torres Strait Islander peoples in Australia, and to identify gaps in the existing literature. Methods A systematic review with narrative synthesis was conducted in accordance with PRISMA 2020 guidelines.
Angus van der Nagel +3 more
wiley +1 more source
The results descemet-stripping automated endothelial keratoplasty at bullous keratopathy [PDF]
Purpose: to evaluate outcomes of the descemet-stripping automated endothelial keratoplasty using eye drops Kombinil-Duo dur- ing postoperative period.Methods: 26 patients suffered from bullous keratopathy underwent descemet-stripping automated ...
S. V. Trufanov
core +1 more source
Purpose: We describe a combined Descemet Membrane Endothelial Keratoplasty (DMEK) using the Cornea-press (C-Press) technique, with implantation of a new sutureless, scleral fixated intraocular lens (IOL) (Carlevale, Soleko), in a case of bullous ...
Wassim Ghazal +4 more
doaj +1 more source
Comparison of treatments for bullous keratopathy in rabbits
The aim of the present study was to compare deep lamellar endothelial keratoplasty (DLEK) and penetrating keratoplasty (PK) treatments for bullous keratopathy (BK). In total, 36 healthy New Zealand white rabbits were randomly divided into 3 groups termed the experimental, DLEK and PK groups. The experimental control group received no treatment.
ZHAO, HAIXIA +3 more
openaire +3 more sources
Exploring the histopathological signature of repeat‐mediated Fuchs endothelial corneal dystrophy
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Anne‐Marie S. Kladny +5 more
wiley +1 more source
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang +9 more
wiley +1 more source

