Results 51 to 60 of about 17,747 (199)

Transplantation of iPSC-derived corneal endothelial substitutes in a monkey corneal edema model

Stem Cell Research, 2021
Objective: In order to provide regenerative therapy for millions of patients suffering from corneal blindness globally, we derived corneal endothelial cell substitute (CECSi) cells from induced pluripotent stem cells (iPSCs) to treat corneal edema due to
Shin Hatou, Tomoko Sayano, Kazunari Higa, Emi Inagaki, Yuji Okano, Yasunori Sato, Hideyuki Okano, Kazuo Tsubota, Shigeto Shimmura   +8 more
doaj   +1 more source

The Expression of Human Corneal MMP-2, MMP-9, proMMP-13 and TIMP-1 in Bullous Keratopathy and Keratoconus [PDF]

, 2008
We aim to find a link between keratokonus (KC) and bullous keratopathy (BK), and extra cellular matrix re-modellation molecules. The activities of matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), pro-matrix metalloproteinase-13 ...
Romac, Ivana, Dekaris, Iva, Balog, Tihomir, Gabrić, Nikica, Bohač, Maja, Marotti, Tanja, Predović, Jurica   +6 more
core   +1 more source

Histology of corneal wound healing after deep lamellar endothelial keratoplasty

Clinical Ophthalmology, 2008
Chaoran Zhang1, Jianjiang Xu1, Rongjia Chen21Ophthalmology Department, 2Pathology Department, Eye and Ear Nose Throat Hospital, Fudan University, Shanghai, ChinaAbstract: Deep lamellar endothelial keratoplasty (DLEK) has become an alternative procedure ...
Chaoran Zhang, Jianjiang Xu, Rongjia Chen   +2 more
doaj  

Generation of a Novel Col8a2P2A‐CreERT2 Mouse Line Enables Targeted Genetic Manipulation of Corneal Endothelial Cells and Modeling of Endothelial Decompensation

genesis, Volume 64, Issue 2, April 2026.
ABSTRACT The corneal endothelium is a monolayer of specialized cells that maintains stromal deturgescence and transparency, functions essential for vision. Despite its clinical importance, the developmental origins and homeostatic programs of the endothelium remain poorly understood, in part due to the lack of a lineage‐specific genetic driver.
Yong Yuan, Josiah Holt, Samuel Lorry, Yen‐Chiao Wang, Yueh‐Chiang Hu, Zhixing Ma, Adam Kaufman, Winston Kao, Diego G. Ogando, Chia‐Yang Liu   +9 more
wiley   +1 more source

Superficial Keratectomy and Conjunctival Advancement Hood Flap (SKCAHF) for the Management of Bullous Keratopathy [PDF]

, 2016
PURPOSE: To evaluate the efficacy of superficial keratectomy and conjunctival advancement hood flap (SKCAHF) for the treatment of bullous keratopathy in canine patients.
Thomasy, Sara M, Calderon, Allison S, Linton, Lana L, Murphy, Christopher J, Stanley, Amelia A, Horikawa, Taemi, Li, Jennifer   +6 more
core   +1 more source

Perfil do paciente com ceratopatia bolhosa pós-facectomia atendidos em hospital público Profile of patient with aphakic/pseudopfakic bullous keratopaty attended at public hospital

Revista Brasileira de Oftalmologia, 2009
Objetivo: Identificar e analisar criticamente o perfil dos pacientes com ceratopatia bolhosa atendidos em um hospital municipal. Métodos: Foi realizada análise retrospectiva de 35 olhos de 35 pacientes em acompanhamento no setor de córnea e doenças ...
Marcony Rodrigues de Santhiago, Luiz Alberto Molina Monica, Newton Kara-Junior, Beatriz de Abreu Fiúza Gomes, Pedro Moreira Bertino, Maysa Godoy Gomes Mazurek, Yoshifume Yamane, Sergio Henrique Sampaio Meirelles   +7 more
doaj   +1 more source

Prevalence and Characteristics of Feline Ulcerative Keratitis and Corneal Sequestra in a Referral Population and Comparison Between Brachycephalic and Nonbrachycephalic Cats

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objectives To investigate the prevalence and characteristics of feline ulcerative keratitis (UK) and corneal sequestra (CS) in brachycephalic and nonbrachycephalic breeds. Animals Studied Brachycephalic and nonbrachycephalic cats. Procedures Cats diagnosed with UK or CS (Total, 392; UK, 290; CS, 102), between 2013 and 2022, were included ...
M. Frejlich, G. Payen
wiley   +1 more source

Effects of COVID‐19 on Corneal Transplants Across the Five Regions of Brazil and Trends in Post‐Pandemic Recovery—A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims The COVID‐19 pandemic significantly disrupted global eye health services, including corneal transplants. This study evaluates the pandemic's long‐term impact on corneal transplantation across Brazil's five regions, highlighting national and regional recovery trends.
Josue Geraldo Lessa, Amélia Soares de Melo, Leandro Vassuler Baldon, Bernardo G. L. Carvalho, Nathalia Sernizon Guimaraes, Aleida N. Soares, Bruno Lovaglio Cançado Trindade, Fernanda Ludolf   +7 more
wiley   +1 more source

P53, CD95, cathepsin and survivin pathways in Fuchs dystrophy and pseudophakic bullous keratopathy corneas [PDF]

, 2008
Our purpose was to elucidate the pathways of apoptosis of corneas with Fuchs’ dystrophy and pseudophakic bullous keratopathy. Sixteen corneal buttons (14 patients, median age 73 years) with Fuchs’ dystrophy, 13 with pseudophakic bullous keratopathy (
Süveges, Ildiko, Szende, Béla, Szentmáry, Nora   +2 more
core  

Descemet Stripping Automated Endothelial Keratoplasty for Treatment of Pseudophakic Bullous Keratopathy

, 2012
Pur po se: To evaluate the results and complications of Descemet stripping automated endothelial keratoplasty (DSAEK) in the treatment of pseudophakic bullous keratopathy (PBK).
Selin Tuğtan, Banu Torun Acar, Suphi Acar   +2 more
core   +1 more source