Results 71 to 80 of about 6,059 (217)

Effectiveness and safety of endothelial keratoplasty for pseudophakic and aphakic bullous keratopathy: a systematic review of randomized controlled trials and cohort studies

Revista Brasileira de Oftalmologia, 2016
Objective: For nearly a century, penetrating keratoplasty has been the surgical technique of choice in the management of corneal changes. However, in recent years, several lamellar keratoplasty techniques have been developed, modified or improved ...
Bruno Harfuch, Amélia Kamegasawa, Larissa S Harfuch, Victor Andrigheti Coronado Antunes   +3 more
doaj   +1 more source

Illuminating Blurry Vision: Visualization of Corneal Protein Deposition With Immunofluorescence in Two Illustrative Case Reports

Case Reports in Pathology, Volume 2026, Issue 1, 2026.
Background Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic, premalignant disease with a progression rate of 0.5%–1% per year to multiple myeloma. It can rarely present with significant ocular symptoms in the context of crystalline keratopathy, necessitating medical and surgical interventions.
Sena Zengin, Chaow Charoenkijkajorn, David Warner, T. David Bourne, Daisy Alapat, Neriman Gokden, Murat Gokden, Stephen Nix, Suraiya Saleem   +8 more
wiley   +1 more source

Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion. [PDF]

, 2020
The advent of cell culture-based methods for the establishment and expansion of human corneal endothelial cells (CEnC) has provided a source of transplantable corneal endothelium, with a significant potential to challenge the one donor-one recipient ...
Aldave, Anthony J, Azimov, Rustam, Boere, Payton M, Chung, Doug D, Frausto, Ricardo F, George, Benjamin L, Hanser, E Maryam, Kao, Liyo, Kurtz, Ira, Mehta, Jodhbir S, Morselli, Marco, Peh, Gary SL, Pellegrini, Matteo, Swamy, Vinay S, Wu, Jessica   +14 more
core  

Decreased Corneal Endothelial Cell Apoptosis Due to U/S Power Injury With Limbal Mesenchymal Stem Cell Secretome Therapy

Stem Cells International, Volume 2026, Issue 1, 2026.
Purpose To evaluate the effects of limbal mesenchymal stem cell secretome (LMSC‐S) on corneal endothelial NF‐κB, TNF‐α, and Caspase‐8 expression after U/S power injury of the phacoemulsification machine. Setting Stem Cell Research and Development Center, Universitas Airlangga. Design Experimental studies on laboratory animals.
Dicky Hermawan, I. Ketut Sudiana, Fedik Abdul Rantam, Evelyn Komaratih, Harleen Khatra   +4 more
wiley   +1 more source

Assessment of the use of cryopreserved x freeze-dried amniotic membrane (AM) for reconstruction of ocular surface in rabbit model [PDF]

, 2008
Purpose: To determine the efficacy of freeze-dried amniotic membrane (AM) for reconstruction of the ocular surface in rabbit eyes. Methods: the sterilized, freeze-dried amniotic membrane (lyophilized or FD-AM) is a preservative method that uses the ...
Cristovam, Priscila, Haapalainen, Edna Freymuller, Libera, Rodrigo Doyle, Lima, Acacio de Souza, Melo, Gustavo Barreto de, Pereira Gomes, Jose Alvaro   +5 more
core   +3 more sources

Drug‐Induced Periocular and Ocular Surface Disorders: An EAACI Position Paper

Allergy, Volume 80, Issue 11, Page 2953-2972, November 2025.
ABSTRACT Various systemic and topical medications can induce ocular and periocular cutaneous adverse effects (AEs), ranging from mild to severe. These AEs may lead to ocular surface (OS) damage and, in some cases, life‐threatening complications. Drug‐induced ocular adverse reactions are generally classified into two primary categories: toxic reactions ...
Andrea Leonardi, Banu Bozkurt, Diana Silva, Charlotte G. Mortz, Christophe Baudouin, Marina Atanaskovic‐Markovic, Vibha Sharma, Serge Doan, Shweta Agarwal, Daniel Pérez‐Formigo, Maria Joao Vasconcelos, Francoise‐Brignole Baudouin, Gonzalo Chorzepa, Jean‐Luc Fauquert, Virginia Calder, Pascal Demoly, Luis Delgado   +16 more
wiley   +1 more source

Success and complication rates of trabeculectomies augmented with MMC in the management of glaucoma [PDF]

, 2010
Glaucoma unresponsive to medical treatment is managed by surgery. Augmentation with mitomycin C (MMC) is considered in patients at high risk of surgery failure.
Mercieca, Franco, Sciriha, Gabriella M.
core  

Corneal Cell Matrix‐Conditioned Amniotic Membrane with Improved Biochemical Properties and Corneal Wound Healing Potential: An In Vitro and In Vivo Study

Macromolecular Materials and Engineering, Volume 310, Issue 6, June 2025.
In this research, the amniotic membrane is sought to be enhanced biologically by treating it with primary cultured corneal cells. The findings indicate that amniotic membranes conditioned with limbal stem cells serve as an effective wound dressing that mimics corneal tissue, offering better cell adhesion, and healing properties, paving the way for ...
Zeinab Nokhbedehghan, Zahra Esmaeili, Seyed‐Hashem Daryabari, Hossein Aghamollaei, Sara Simorgh, Jila Majidi, Sanaz Alizadeh, Sadjad Khosravimelal, Narendra Pal Singh Chauhan, Hajar Nasiri, Mazaher Gholipourmalekabadi   +10 more
wiley   +1 more source

Amniotic membrane transplantation [PDF]

, 2000
Amniotic membrane transplantation has been used as an alternative for ocular surface reconstruction. Indications for amniotic membrane transplantation include persistent epithelial defects, pterygium, Stevens-Johnson syndrome, ocular cicatricial ...
Moreira, Hamilton, Oliveira, Cinara S. De   +1 more
core   +2 more sources

Japan's Conditional/Time‐Limited Early Approval System in Regenerative Medicine: A Case Study of Rise and Falls of Autologous Skeletal Myoblast Sheets

Clinical Pharmacology &Therapeutics, Volume 117, Issue 5, Page 1171-1174, May 2025.
Japan's conditional/time‐limited early approval program, initiated in 2014, aimed to advance regenerative medicine by expediting market access. However, the withdrawal of autologous skeletal myoblast sheets (Heartsheet) due to ineffectiveness raises concerns about the balance between rapid approval and scientific integrity.
Hayase Hakariya, Akihiko Ozaki, Yudai Kaneda, Tetsuya Tanimoto   +3 more
wiley   +1 more source