Results 1 to 10 of about 135,122 (302)

The Role of Rho Kinase Inhibitors in Corneal Diseases [PDF]

Drug Design, Development and Therapy
Stefan Futterknecht,1,2 Eleftherios Chatzimichail,1 Konstantin Gugleta,1,3 Georgios D Panos,4,5,* Zisis Gatzioufas1,3,* 1Department of Ophthalmology, University Hospital of Basel, Basel, Switzerland; 2Institute of Molecular and Clinical ...
Futterknecht S, Chatzimichail E, Gugleta K, Panos GD, Gatzioufas Z   +4 more
doaj   +4 more sources

Adeno-Associated Virus Mediated Gene Therapy for Corneal Diseases [PDF]

Pharmaceutics, 2020
According to the World Health Organization, corneal diseases are the fourth leading cause of blindness worldwide accounting for 5.1% of all ocular deficiencies. Current therapies for corneal diseases, which include eye drops, oral medications, corrective
Prabhakar Bastola, Liujiang Song, Brian C. Gilger, Matthew L. Hirsch   +3 more
doaj   +4 more sources

Artificial intelligence and corneal diseases. [PDF]

Curr Opin Ophthalmol, 2022
Purpose of review Artificial intelligence has advanced rapidly in recent years and has provided powerful tools to aid with the diagnosis, management, and treatment of ophthalmic diseases. This article aims to review the most current clinical artificial intelligence applications in anterior segment diseases, with an emphasis on ...
Kang L, Ballouz D, Woodward MA.
europepmc   +3 more sources

Methylation in cornea and corneal diseases: a systematic review [PDF]

Cell Death Discovery
Corneal diseases are among the primary causes of blindness and vision loss worldwide. However, the pathogenesis of corneal diseases remains elusive, and diagnostic and therapeutic tools are limited.
Yutong Xia, Kuangqi Chen, Qianjie Yang, Zhitong Chen, Le Jin, Liyue Zhang, Xin Yu, Liyin Wang, Chen Xie, Yuan Zhao, Ye Shen, Jianping Tong   +11 more
doaj   +2 more sources

Corneal Disease & Transplantation

Journal of Clinical Medicine, 2022
Corneal diseases represent the third leading cause of blindness worldwide, and corneal transplantation, which aims at restoring corneal clarity and vision, is the most frequently performed transplant worldwide [...]
Giulia Coco, Vito Romano
openaire   +5 more sources

Early Visibility of Cellular Aggregates and Changes in Central Corneal Thickness as Predictors of Successful Corneal Endothelial Cell Injection Therapy

Cells, 2023
(1) Background: Cell injection therapy is an emerging treatment for bullous keratopathy (BK). Anterior segment optical coherence tomography (AS-OCT) imaging allows the high-resolution assessment of the anterior chamber. Our study aimed to investigate the
Evan N. Wong, Valencia H. X. Foo, Gary S. L. Peh, Hla M. Htoon, Heng-Pei Ang, Belinda Y. L. Tan, Hon-Shing Ong, Jodhbir S. Mehta   +7 more
doaj   +1 more source

Advances in clinical examination of lacrimal gland

Frontiers in Medicine, 2023
In humans, the lacrimal gland is located in the socket of the frontal bone above the outer orbital area. As an essential part of the eye surface, the gland is fixed to the orbital periosteum by connective tissue.
Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou   +20 more
doaj   +1 more source

The Effects of Donor-Recipient Age and Sex Compatibility in the Outcomes of Deep Anterior Lamellar Keratoplasties

Frontiers in Medicine, 2022
PurposeCorneal transplantations are the commonest allogenic transplant surgeries performed worldwide. Transplantable grade donor cornea is a finite resource.
Hon Shing Ong, Hon Shing Ong, Hon Shing Ong, Nathalie Chiam, Hla Myint Htoon, Hla Myint Htoon, Ashish Kumar, Anshu Arundhati, Anshu Arundhati, Jodhbir S. Mehta, Jodhbir S. Mehta, Jodhbir S. Mehta, Jodhbir S. Mehta   +12 more
doaj   +1 more source

Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK)

Journal of Ophthalmology, 2022
The corneal endothelium has a crucial role in maintaining a clear and healthy cornea. Corneal endothelial cell loss occurs naturally with age; however, a diagnosis of glaucoma and surgical intervention for glaucoma can exacerbate a decline in cell number
Neeru A Vallabh, Stephnie Kennedy, Riccardo Vinciguerra, Keri McLean, Hannah Levis, Davide Borroni, Vito Romano, Colin E Willoughby   +7 more
doaj   +1 more source

In vivo confocal microscopy qualitative investigation of the relationships between lattice corneal dystrophy deposition and corneal nerves

BMC Ophthalmology, 2021
Background To investigate the corneal neurotropic phenomenon in patients with lattice corneal dystrophy (LCD) with in vivo laser scanning confocal microscopy (IVCM).
Fengjiao Zhu, Ming Li, Chun Zhang, Chan Chen, Fangwei Ying, Danyao Nie   +5 more
doaj   +1 more source