Results 1 to 10 of about 90,437 (193)

Adeno-Associated Virus Mediated Gene Therapy for Corneal Diseases [PDF]

open access: yesPharmaceutics, 2020
According to the World Health Organization, corneal diseases are the fourth leading cause of blindness worldwide accounting for 5.1% of all ocular deficiencies. Current therapies for corneal diseases, which include eye drops, oral medications, corrective
Prabhakar Bastola   +3 more
doaj   +5 more sources

Nanomedicine Approaches for Corneal Diseases [PDF]

open access: yesJournal of Functional Biomaterials, 2015
Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions. However, barrier properties of the ocular surface necessitate high concentration of the drugs applied in the eye ...
Shyam S Chaurasia   +2 more
exaly   +5 more sources

Methylation in cornea and corneal diseases: a systematic review [PDF]

open access: yesCell Death Discovery
Corneal diseases are among the primary causes of blindness and vision loss worldwide. However, the pathogenesis of corneal diseases remains elusive, and diagnostic and therapeutic tools are limited.
Yutong Xia   +11 more
doaj   +3 more sources

The Role of Rho Kinase Inhibitors in Corneal Diseases [PDF]

open access: yesDrug Design, Development and Therapy
Stefan Futterknecht,1,2 Eleftherios Chatzimichail,1 Konstantin Gugleta,1,3 Georgios D Panos,4,5,* Zisis Gatzioufas1,3,* 1Department of Ophthalmology, University Hospital of Basel, Basel, Switzerland; 2Institute of Molecular and Clinical ...
Futterknecht S   +4 more
doaj   +4 more sources

Corneal Disease & Transplantation [PDF]

open access: yesJournal of Clinical Medicine, 2022
Corneal diseases represent the third leading cause of blindness worldwide, and corneal transplantation, which aims at restoring corneal clarity and vision, is the most frequently performed transplant worldwide [...]
Giulia Coco, Vito Romano
openaire   +6 more sources

Artificial intelligence and corneal diseases. [PDF]

open access: yesCurr Opin Ophthalmol, 2022
Purpose of review Artificial intelligence has advanced rapidly in recent years and has provided powerful tools to aid with the diagnosis, management, and treatment of ophthalmic diseases. This article aims to review the most current clinical artificial intelligence applications in anterior segment diseases, with an emphasis on ...
Kang L, Ballouz D, Woodward MA.
europepmc   +3 more sources

Cell Therapy of Corneal Diseases. [PDF]

open access: yesCornea, 2016
Mesenchymal stem cells isolated from connective tissues are pluripotent and differentiate into phenotypes of connective tissue cell lineages (osteoblasts, chondrocytes, and adipocytes) in vitro and in vivo. They have been used to treat mouse models of connective tissue disease such as lumican-null (Lum) and mucopolysaccharidosis (Gusb) mice ...
Kao WW, Coulson-Thomas VJ.
europepmc   +4 more sources

Mesenchymal Stem Cells and Exosomes: A Novel Therapeutic Approach for Corneal Diseases [PDF]

open access: yesInternational Journal of Molecular Sciences, 2023
Se-Heon Oh, Ho Seok Chung, Hun Lee
exaly   +2 more sources

Early Visibility of Cellular Aggregates and Changes in Central Corneal Thickness as Predictors of Successful Corneal Endothelial Cell Injection Therapy

open access: yesCells, 2023
(1) Background: Cell injection therapy is an emerging treatment for bullous keratopathy (BK). Anterior segment optical coherence tomography (AS-OCT) imaging allows the high-resolution assessment of the anterior chamber. Our study aimed to investigate the
Evan N. Wong   +7 more
doaj   +1 more source

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