Results 11 to 20 of about 2,181,842 (257)

Nanomedicine Approaches for Corneal Diseases [PDF]

Journal of Functional Biomaterials, 2015
Corneal diseases are the third leading cause of blindness globally. Topical nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, antibiotics and tissue transplantation are currently used to treat corneal pathological conditions. However, barrier properties of the ocular surface necessitate high concentration of the drugs applied in the eye ...
Lakshminarayanan R, Shyam Chaurasia, Rajiv Mohan   +2 more
exaly   +5 more sources

Corneal nerves in health and disease [PDF]

Progress in Retinal and Eye Research, 2019
The cornea is the most sensitive structure in the human body. Corneal nerves adapt to maintain transparency and contribute to corneal health by mediating tear secretion and protective reflexes and provide trophic support to epithelial and stromal cells.
Mouhamed A. Al-Aqaba, Virinder K. Dhillon, Imran Mohammed, Dalia G. Said, Harminder S. Dua   +4 more
openaire   +4 more sources

Effects of Aberrant Pax6 Gene Dosage on Mouse Corneal Pathophysiology and Corneal Epithelial Homeostasis [PDF]

, 2011
Background: Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6(+/-) heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal ...
Fullwood, Nigel J., Martin, Francis L., Collinson, J. Martin, Richard L Mort, Morley, Steven D., Morley Steven D., West John D., Bentley, Adam J., Adam J Bentley, Mort, Richard L, Collinson J. Martin, Panagiotis Douvaras, Collinson, J Martin, J Martin Collinson, Bentley Adam J., Mort Richard L., Martin, Francis L, Bentley, Adam J, Morley, Steven D, Martin Francis L., Douvaras, Panagiotis, Steven D Morley, Robert E Hill, Mort, Richard L., West, John D., Hill, Robert E, Fullwood, Nigel J, Nigel J Fullwood, Douvaras Panagiotis, Fullwood Nigel J., Francis L Martin, Hill Robert E., Hill, Robert E., West, John D, John D West   +34 more
core   +5 more sources

Methylation in cornea and corneal diseases: a systematic review

Cell Death Discovery
Corneal diseases are among the primary causes of blindness and vision loss worldwide. However, the pathogenesis of corneal diseases remains elusive, and diagnostic and therapeutic tools are limited.
Yutong Xia, Kuangqi Chen, Qianjie Yang, Zhitong Chen, Le Jin, Liyue Zhang, Xin Yu, Liyin Wang, Chen Xie, Yuan Zhao, Ye Shen, Jianping Tong   +11 more
doaj   +2 more sources

Corneal Disease & Transplantation

Journal of Clinical Medicine, 2022
Corneal diseases represent the third leading cause of blindness worldwide, and corneal transplantation, which aims at restoring corneal clarity and vision, is the most frequently performed transplant worldwide [...]
Giulia Coco, Vito Romano
openaire   +5 more sources

Early Visibility of Cellular Aggregates and Changes in Central Corneal Thickness as Predictors of Successful Corneal Endothelial Cell Injection Therapy

Cells, 2023
(1) Background: Cell injection therapy is an emerging treatment for bullous keratopathy (BK). Anterior segment optical coherence tomography (AS-OCT) imaging allows the high-resolution assessment of the anterior chamber. Our study aimed to investigate the
Evan N. Wong, Valencia H. X. Foo, Gary S. L. Peh, Hla M. Htoon, Heng-Pei Ang, Belinda Y. L. Tan, Hon-Shing Ong, Jodhbir S. Mehta   +7 more
doaj   +1 more source

Advances in clinical examination of lacrimal gland

Frontiers in Medicine, 2023
In humans, the lacrimal gland is located in the socket of the frontal bone above the outer orbital area. As an essential part of the eye surface, the gland is fixed to the orbital periosteum by connective tissue.
Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou   +20 more
doaj   +1 more source

The Effects of Donor-Recipient Age and Sex Compatibility in the Outcomes of Deep Anterior Lamellar Keratoplasties

Frontiers in Medicine, 2022
PurposeCorneal transplantations are the commonest allogenic transplant surgeries performed worldwide. Transplantable grade donor cornea is a finite resource.
Hon Shing Ong, Hon Shing Ong, Hon Shing Ong, Nathalie Chiam, Hla Myint Htoon, Hla Myint Htoon, Ashish Kumar, Anshu Arundhati, Anshu Arundhati, Jodhbir S. Mehta, Jodhbir S. Mehta, Jodhbir S. Mehta, Jodhbir S. Mehta   +12 more
doaj   +1 more source

Corneal Endothelial Cell Loss in Glaucoma and Glaucoma Surgery and the Utility of Management with Descemet Membrane Endothelial Keratoplasty (DMEK)

Journal of Ophthalmology, 2022
The corneal endothelium has a crucial role in maintaining a clear and healthy cornea. Corneal endothelial cell loss occurs naturally with age; however, a diagnosis of glaucoma and surgical intervention for glaucoma can exacerbate a decline in cell number
Neeru A Vallabh, Stephnie Kennedy, Riccardo Vinciguerra, Keri McLean, Hannah Levis, Davide Borroni, Vito Romano, Colin E Willoughby   +7 more
doaj   +1 more source

Corneal Opacity in LCAT Disease [PDF]

Cornea, 1992
Deficiency of lecithin:cholesterol acyltransferase, LCAT disease, is one of the dyslipoproteinemias with characteristic lipid deposits in the cornea. The present report documents the clinicopathologic abnormalities of one case in which a full-thickness corneal specimen was obtained at the time of corneal transplantation.
Cogan, David G., Kruth, Howard S., Datilis, Manuel B., Martin, Neil   +3 more
openaire   +2 more sources