Results 91 to 100 of about 36,570 (264)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Geometric scaling of elastic pp cross section at the LHC
Physics Letters BWe show that geometric scaling conjectured and observed at the ISR more than 50 years ago, still holds at the LHC. We discuss regularities of the dip - bump structures of the differential elastic cross sections, emphasizing the fact that the ratio of ...
Michał Praszałowicz
doaj +1 more source
In this activity, students focus on the physical and chemical processes associated with the Charleston Bump, a series of rocky scarps, mounds, overhangs, and flat pavements that rise from more than 700 m at the surface of the Blake Plateau to within 400 ...
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 1889 Members of the Bump family in 1889 in Salisbury, Vermont. Pictured are Cyrus Bump (holding baby) born March 6, 1979, Orlo Myron Bump (right) born May 22, 1892, William Fenner Bump (center) born March 16, 1862, and Ermina Louise Bump (baby) born April 8 ...
core
Respon Masyarakat Tergadap Pengembangan BUMP [PDF]
, 2014 Badan Usaha Milik Petani (BUMP) merupakan sebuah inovasi kelembagaan yang dikembangkan oleh FACILITATOR di Kabupaten Sukoharjo. Sebagai inovasi kelembagaan, BUMP merupakan Badan Usaha berbentuk Perseroan, tetapi dalam operasionalisasinya merupakan ...
Utami, Bakti Wahyu +3 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2001 In this paper we present a method that automatically synthesizes bump maps at arbitrary levels of detail in real-time. The only input data we require is a normal density function; the bump map is generated according to that function.
Seidel, Hans-Peter +2 more
core +1 more source