Results 201 to 210 of about 123,640 (305)

Complete left bundle branch block resolution during treatment with Mavacamten: a case report of a first-in-class scenario. [PDF]

Eur Heart J Case Rep
Marchionni G, Alfarano M, Ballatore F, Costantino J, Chimenti C.   +4 more
europepmc   +1 more source

On the Origins of Toughness in Corymbia calophylla (Marri Tree) Nuts

Advanced Science, EarlyView.
We uncover the natural toughening mechanisms of the marri nut, including fiber pullout, crack deflection, and a viscoelastic matrix, which enable exceptional energy absorption and ductility comparable to Teflon, with an elastic modulus similar to acrylic.
Wegood M. Awad, Ahmed S. Dalaq, Marieh B. Al‐Handawi, Rezo Getsadze, Oraib Al‐Ketan, James Weston, Mohammed Daqaq, Panče Naumov   +7 more
wiley   +1 more source

Baseline right bundle branch block and clinical outcomes in patients undergoing transcatheter aortic valve implantation: a Danish nationwide cohort study. [PDF]

Eur Heart J Open
Steiner DK, Krogager ML, Polcwiartek C, Graff C, Christensen HC, Andersen MP, Terkelsen CJ, Christiansen EH, Nielsen JC, Kronborg MB, Sommer AM, Thim T, Ellert J, Johansen JB, Bieliauskas G, De Backer O, Vinther M, Simonsen C, Riahi S, Riddersholm SJ, Torp-Pedersen C, Kragholm KH, Eftekhari A.   +22 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Treatment strategies and prognosis of complete left bundle branch block after transcatheter closure of ventricular septal defect in pediatrics. [PDF]

BMC Cardiovasc Disord
Li YF, Ma BY, Chen ZW, Wang SS, Zhang ZW, Xie YM.   +5 more
europepmc   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Flash Pulmonary Edema Triggered by Tadalafil Use in a Patient With Chronic Left Bundle Branch Block. [PDF]

Cureus
Roytenberg R, Zamudio Herrera OR.
europepmc   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Left Bundle Branch Block as a Risk Factor for Heart Failure.

JAMA Netw Open
Thein AS, Dixit S, Soliman EZ, Heckbert SR, Psaty BM, Gottdiener J, Marcus GM.   +6 more
europepmc   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source