Results 1 to 10 of about 116,355 (206)

Development and Function of the Cardiac Conduction System in Health and Disease [PDF]

Journal of Cardiovascular Development and Disease, 2017
The generation and propagation of the cardiac impulse is the central function of the cardiac conduction system (CCS). Impulse initiation occurs in nodal tissues that have high levels of automaticity, but slow conduction properties.
David S. Park, Glenn I. Fishman
doaj   +7 more sources

Prevalence of cardiac fibrosis and infiltrative cardiomyopathy in patients with advanced conduction system disease

Journal of Arrhythmia
Background Conduction system disease may represent an early manifestation of underlying structural heart disease, including infiltrative disorders.
Jeremy William, Haider Muthana, Joseph Hogarty, Andrew Taylor, James L. Hare, Justin Mariani, Hitesh Patel, Geoff Wong, Dion Stub, David M. Kaye, Sandeep Prabhu, Peter M. Kistler, Aleksandr Voskoboinik   +12 more
doaj   +6 more sources

Impact of functional studies on exome sequence variant interpretation in early-onset cardiac conduction system diseases [PDF]

Cardiovascular Research, 2020
Aims The genetic cause of cardiac conduction system disease (CCSD) has not been fully elucidated. Whole-exome sequencing (WES) can detect various genetic variants; however, the identification of pathogenic variants remains a challenge.
Asano, Yoshihiro, Beerens, Manu, Burch, Micah L, Buys, Eva, Chiang, David Y, Cui, Shihe, Fujino, Noboru, Fujita, Takashi, Funada, Akira, Furusho, Hiroshi, Hayashi, Kenshi, Hodatsu, Akihiko, Inoue, Masaru, Kaku, Bunji, Kato, Takeshi, Kawashiri, Masa-aki, Kelly, Amy E, Kita, Yoshihito, Kiviniemi, Tuomas O, Kobayashi, Isao, Konno, Tetsuo, Kurata, Yasutaka, MacRae, Calum A, Nagata, Yoji, Nakanishi, Chiaki, Namura, Masanobu, Nomura, Akihiro, Oe, Kotaro, Okada, Hirofumi, Onoue, Kenji, Saito, Yoshihiko, Sakamoto, Yuichiro, Sakata, Kenji, Sips, Patrick, Tada, Hayato, Takamura, Masayuki, Takashima, Seiji, Takeda, Yuko, Tanaka, Yoshihiro, Teramoto, Ryota, Tsuchiya, Taketsugu, Tsuda, Toyonobu, Usuda, Keiich, Yamagishi, Masakazu, Zhao, Yanbin   +44 more
core   +6 more sources

Is there an association between Fahr′s disease and cardiac conduction system disease?: A case report

Journal of Research in Medical Sciences, 2012
Background: Fahr′s disease is a rare neurodegenerative disorder of unknown cause characterized by idiopathic basal ganglia calcification that is associated with neuropsychiatric and cognitive impairment.
Prashanth Panduranga, Kadhim Sulaiman
doaj   +5 more sources

Conduction System Pacing Versus Conventional Cardiac Resynchronization Therapy in Congenital Heart Disease [PDF]

JACC: Clinical Electrophysiology, 2022
Dyssynchrony-associated left ventricular systolic dysfunction is a major contributor to heart failure in congenital heart disease (CHD). Although conventional cardiac resynchronization therapy (CRT) has shown benefit, the comparative efficacy of cardiac conduction system pacing (CSP) is unknown.The purpose of this study was compare the clinical ...
Jeremy P. Moore, Natasja M.S. de Groot, Matthew O’Connor, Daniel Cortez, Jonathan K. Su, Austin Burrows, Kevin Shannon, Edward T. O’Leary, Maully J. Shah, Paul Khairy, Joseph Atallah, Tom Wong, Michael S. Lloyd, Yannick J.H.J. Taverne, Anne M. Dubin, Jens Cosedis Nielsen, Reinder Evertz, Richard J. Czosek, Malini Madhavan, Philip M. Chang, Alper Aydın, Óscar Cano   +21 more
openalex   +6 more sources

Adolescent with Unexplained Cardiac Hypertrophy, Ventricular Pre-Excitation, Conduction System Disease: PRKAG2 Cardiac Syndrome as a Rare Mimicker of Hypertrophic Cardiomyopathy. [PDF]

Anatol J Cardiol
Guo Y, Yi D, Liu D, Fan Q, Ma Z, Wang L, Chen H, Wang B, Yan H.   +8 more
europepmc   +5 more sources

High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling [PDF]

Scientific Reports, 2017
Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
Robert S. Stephenson, Andrew Atkinson, Petros Kottas, Filip Perde, Fatemeh Jafarzadeh, Mike Bateman, Paul A. Iaizzo, Jichao Zhao, Henggui Zhang, Robert H. Anderson, Jonathan C. Jarvis, Halina Dobrzynski   +11 more
doaj   +2 more sources

Rapidly Progressive Cardiac Manifestation of Behçet's Disease Involving Conduction System and Aortic Valve [PDF]

Journal of Cardiovascular Ultrasound, 2011
Cardiac conduction system impairment is a rare clinical manifestation of Behçet's disease. We report a patient who showed 1st degree atrioventricular block at first presentation, and showed aggravated finding of 3rd degree atrioventricular block on five months later.
Jin Yu, Eun Joo Cho, Eun Hye Ji, Hee Sun Kwon, Jin Seok Kim, Kyu Young Choi, Beom June Kwon, Dong‐Bin Kim, Seong Won Jang, Jae Hyung Kim   +9 more
openalex   +4 more sources

Rare SCN10A variants associated with cardiac conduction system diseases [PDF]

European Heart Journal, 2020
Abstract Background The genetic bases of cardiac conduction-system disease (CCSD) range from ion channelopathies to mutations in many other genes. Genome-wide association studies have shown common variants in SCN10A influence cardiac conduction.
Kenshi Hayashi, Noboru Fujino, Hiroshi Furusho, Soichiro Usui, Kenji Sakata, Tamayo Kato, Toshihide Tsuda, Satoru Niwa, Kazuhiko Takeuchi, Masa‐aki Kawashiri, Masayuki Takamura   +10 more
openalex   +2 more sources

Cardiac Hypertrophy, Accessory Pathway, and Conduction System Disease in an Adolescent

Journal of the American College of Cardiology, 2013
We present the case of PRKAG2 cardiac syndrome, a rare autosomal-dominant genetic disease characterized by peculiar clinical and electrophysiological abnormalities. We clearly show through the images the peculiar clinical features that should raise suspicion of a mutant PRKAG2 gene. Indeed, together with an accurate clinical and instrumental evaluation,
Enrico Fabris, Francesca Brun, Andrea Giuseppe Porto, Pasquale Losurdo, Laura Vitali Serdoz, Massimo Zecchin, Giovanni Maria Severini, Luisa Mestroni, Antonio Di Chiara, Gianfranco Sinagra   +9 more
  +7 more sources