Results 11 to 20 of about 464 (205)

Zebrafish Models in Therapeutic Research of Cardiac Conduction Disease

Frontiers in Cell and Developmental Biology, 2021
Malfunction in the cardiac conduction system (CCS) due to congenital anomalies or diseases can cause cardiac conduction disease (CCD), which results in disturbances in cardiac rhythm, leading to syncope and even sudden cardiac death.
Rui Gao, Jie Ren
doaj   +3 more sources

Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease [PDF]

Journal of Molecular and Cellular Cardiology, 2008
Mutations in the lamin A/C (LMNA) gene, which encodes nuclear membrane proteins, cause a variety of human conditions including dilated cardiomyopathy (DCM) with associated cardiac conduction system disease. To investigate mechanisms responsible for electrophysiologic and myocardial phenotypes caused by dominant human LMNA mutations, we performed ...
Cordula M, Wolf, Libin, Wang, Ronny, Alcalai, Anne, Pizard, Patrick G, Burgon, Ferhaan, Ahmad, Megan, Sherwood, Dorothy M, Branco, Hiroko, Wakimoto, Glenn I, Fishman, Vincent, See, Colin L, Stewart, David A, Conner, Charles I, Berul, Christine E, Seidman, J G, Seidman   +15 more
openaire   +4 more sources

Desmin variants: Trigger for cardiac arrhythmias?

Frontiers in Cell and Developmental Biology, 2022
Desmin (DES) is a classical type III intermediate filament protein encoded by the DES gene. Desmin is abundantly expressed in cardiac, skeletal, and smooth muscle cells.
Wei Su, Wei Su, Stan W. van Wijk, Stan W. van Wijk, Bianca J. J. M. Brundel, Bianca J. J. M. Brundel   +5 more
doaj   +1 more source

A Case of Complete AV Blockade in Patient with Lyme Borreliosis

Архивъ внутренней медицины, 2022
Lyme disease (tick-borne borreliosis) is an infectious vector-borne natural focal disease that tends to a chronic and recurrent course with a predominant damage to the skin, nervous system, musculoskeletal system and heart. Cardiac features is manifested,
O. N. Denisov, E. V. Efremova, A. A. Nafeev   +2 more
doaj   +1 more source

Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system

The Journal of Clinical Investigation, 2022
Arrhythmogenic cardiovascular disorders are associated with considerable morbidity and mortality. Whether cardiac conduction disease is caused by genetic defects, procedural perturbations, valvular disease, ischemia, aging, or heart failure, new ...
Daniel J. Garry, Demetris Yannopoulos, Tamas Alexy   +2 more
doaj   +1 more source

An unusual ‘bow tie’ image in pacemaker implantation

Indian Pacing and Electrophysiology Journal, 2022
Upper venous system anatomic variations may cause difficulties during cardiac pacemaker implantation. Persistent left superior vena cava (PLSVC) and absent right superior vena cava could be an arrhythmogenic source of atrial arrhythmias and cardiac ...
Oguzhan Ekrem Turan, Resit Yigit Yilancioglu, Ahmet Anil Baskurt, Emin Evren Ozcan   +3 more
doaj   +1 more source

Cardiac conduction system- A detailed study in 46 cases of sudden death

Journal of Pathology of Nepal, 2015
Background: Atherosclerotic coronary artery disease is the modern pandemic and is said to be responsible for a major chunk of sudden cardiac deaths. However, in few cases; especially among the young, conduction system abnormalities were found to be the ...
LM Ilias, MR Pai, S Shukla, A Ponniah, K Gautam, P Vijayan   +5 more
doaj   +1 more source

Left bundle branch pacing: An evolving site for physiological pacing

Journal of Arrhythmia, 2021
For patients with symptomatic bradyarrhythmia, cardiac pacing is the only appropriate treatment option. Electrical and mechanical dyssynchrony caused by traditional right ventricular apical pacing leads to left ventricular dysfunction and atrial ...
Eka P. B. Mulia, Muhammad R. Amadis, Rerdin Julario, Budi B. Dharmadjati   +3 more
doaj   +1 more source

Genetic and physiologic dissection of the vertebrate cardiac conduction system.

PLoS Biology, 2008
Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate chamber contraction and drive blood efficiently and unidirectionally throughout the organism.
Neil C Chi, Robin M Shaw, Benno Jungblut, Jan Huisken, Tania Ferrer, Rima Arnaout, Ian Scott, Dimitris Beis, Tong Xiao, Herwig Baier, Lily Y Jan, Martin Tristani-Firouzi, Didier Y R Stainier   +12 more
doaj   +1 more source

Autopsy for Medical Diagnostics: Finding the Cause of Sudden Unexpected Death through Investigation of the Cardiac Conduction System by Serial Sections

Diagnostics, 2023
Sudden unexpected death (SUD) is a fatal event that occurs in an apparently healthy subject in a way that such an abrupt outcome could have not been predicted.
Giulia Ottaviani, Simone G. Ramos
doaj   +1 more source