Results 41 to 50 of about 122,763 (282)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Masquerading Bundle Branch Block in a Patient with Heart Failure in Nigeria

International Medical Case Reports Journal, 2020
Olumide A Akinyele, Michael O Balogun, Rasaaq A Adebayo, Oladiipo A Olanipekun, Anthony O Akintomide, Oyeronke T Williams, Obafemi S Adesanya Cardiology Unit, Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC), Ile-Ife,
Akinyele OA, Balogun MO, Adebayo RA, Olanipekun OA, Akintomide AO, Williams OT, Adesanya OS   +6 more
doaj  

Analysis of electrocardiographic signs in hypertrophic cardiomyopathy before and after septal myectomy. New criterion for proximal left bundle branch block

Российский кардиологический журнал, 2022
Aim. To analyze 20 electrocardiographic (ECG) signs of left bundle branch block (LBBB) before and after septal myectomy in patients with hypertrophic cardio myopathy (HCM) and develop a criterion for proximal LBBB based on the selected signs.Material and 
L. M. Malishevsky, S. V. Zubarev, A. V. Gurshchenkov, V. K. Lebedeva, T. A. Lyubimtseva, D. S. Malishevskaya, V. V. Zaitsev, M. L. Gordeev, D. S. Lebedev   +8 more
doaj   +1 more source

Numerical simulation of electrocardiograms for full cardiac cycles in healthy and pathological conditions [PDF]

, 2015
This work is dedicated to the simulation of full cycles of the electrical activity of the heart and the corresponding body surface potential. The model is based on a realistic torso and heart anatomy, including ventricles and atria.
Bayés de Luna, Bayés de Luna, Beinart, Bishop, Boulakia, Boulakia, Boulakia, Bourgault, Bueno-Orovio, Buist, Chapelle, Chapelle, Chatterjee, Cohen, Collin, Corrado, Courtemanche, Deng, Ennis, Geuzaine, Harrild, Ho, Ho, Hoekema, Hudsmith, Huiskamp, Huiskamp, Hurtadoa, Jiamsripong, Jiang, Johnson, Keller, Krishnamoorthi, Krueger, Krueger, Lines, Liu, Malmivuo, Martin, Martini, Matsuo, McGuire, Mitchell, Nash, Netter, Nielsen, Ormiston, Potse, Potse, Pullan, Rosner, Sachse, Sovilj, Streeter, Sundnes, Sundnes, Trudel, Wang, Wartak, Wei, Yan, Zwink   +61 more
core   +5 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Peeling off the Mask: Pseudo Myocardial Infarction Pattern on Electrocardiogram During AICD Implantation

Indian Pacing and Electrophysiology Journal, 2015
Lead induced transient right bundle branch block is not uncommon during pacemaker implantation. We describe a patient with old anterior wall myocardial infarction with severe left ventricular dysfunction presenting with recurrent ventricular tachycardia ...
Sudeep Kumar, MD, DM, FACC, FSCAI, Aditya Kapoor, DM, FACC, Nagaraja Moorthy, DM, Yash Lokhandwala, DM, FACC   +3 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Left Bundle Branch Pacing

JACC: Case Reports, 2020
His bundle pacing was developed while seeking a physiological alternative to biventricular cardiac resynchronization therapy. However, His bundle pacing may not be adequate in all patients.
Margarida Pujol-López, MD, Eduard Guasch, MD, PhD, Rafael Jiménez-Arjona, MD, Rodolfo San Antonio, MD, Lluís Mont, MD, PhD, José M. Tolosana, MD, PhD   +5 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Data on association between QRS duration on prehospital ECG and mortality in patients with confirmed STEMI

Data in Brief, 2017
Data presented in this article relates to the research article entitled “Association between QRS duration on prehospital ECG and mortality in patients with suspected STEMI” (Hansen et al., in press) [1].Data on the prognostic effect of automatically ...
Rikke Hansen, Martin Frydland, Ole Kristian Møller-Helgestad, Matias Greve Lindholm, Lisette Okkels Jensen, Lene Holmvang, Hanne Berg Ravn, Jesper Kjærgaard, Christian Hassager, Jacob Eifer Møller   +9 more
doaj   +1 more source