Results 51 to 60 of about 42,821 (262)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Exercise-Induced Bundle Branch Block - an Infrequent Incidence

Nepalese Medical Journal, 2020
We describe an elderly woman who underwent a treadmill test preoperatively and was found to have Exercise-induced Left Bundle Branch Block without chest pain. Coronary angiogram was done which revealed a 70% stenosis in the fi rst diagonal branch of Left
Sheelendra Shakya, Arun Maskey
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

AN INHERITANCE OF IDIOPATHIC CARDIAC CONDUCTION DISORDERS

Российский кардиологический журнал, 2014
Aim. To study relationship of idiopathic atrioventricular and intravenricular disorders of cardiac conductivity with mononucleotide polymorhism (MNP) A/G gene TBX5. Material and methods.
S. S. Tretyakova, S. Yu. Nikulina, V. A. Shulman, A. A. Chernova, V. N. Maksimov, M. I. Voevoda, V. N. Chernov   +6 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Tachycardia with left bundle branch block morphology in a patient with right bundle branch block

Indian Pacing and Electrophysiology Journal
A 35-year-old woman with a history of surgical mitral valve repair at age 16 years, underwent Holter monitoring because of frequent episodes of palpitations.
Ayelet Shauer, Bernard Belhassen
doaj   +1 more source

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

Advanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi, Ebrahim Norouzi, Kostiantyn Hubaiev, Jörg Waitelonis, Harald Sack   +4 more
wiley   +1 more source

PASTA‐ELN: Simplifying Research Data Management for Experimental Materials Science

Advanced Engineering Materials, EarlyView.
Research data management faces ongoing hurdles as many ELNs remain complex and restrictive. PASTA‐ELN offers an open‐source, cross‐platform solution that prioritizes simplicity, offline access, and user control. Its in tuitive folder structure, modular Python add‐ons, and open formats enable seamless documentation, FAIR data practices, and easy ...
S. Brinckmann, G. Winkens, R. Schwaiger
wiley   +1 more source

Compatibility of Methacrylate Based Resins Controls Interfacial Failure and Toughness in 3D‐Printed Multimaterial Composites

Advanced Engineering Materials, EarlyView.
This work shows that the mechanical performance of multimaterial digital light processing (DLP) printed thermoset composites is governed by resin compatibility and interfacial design rather than spatial patterning alone. Brittle and ductile resin combinations produced premature interfacial failure, while graded interfaces and mechanically compatible ...
Ahmed M. H. Ibrahim, Li Meng, Ahmad R. Najafi, Nicolas J. Alvarez   +3 more
wiley   +1 more source

Quantifying CineECG Output for Enhancing Electrocardiography Signals Classification

IEEE Open Journal of Engineering in Medicine and Biology
CineECG, a vectorcardiography-based method, uses standard 12-lead electrocardiography and 3D heart and torso models to depict the electrical activation path during the heart cycle, offering detailed visualization of cardiac electrical activity without ...
MHD Jafar Mortada, Agnese Sbrollini, Ilaria Marcantoni, Erica Iammarino, Laura Burattini, Peter Van Dam   +5 more
doaj   +1 more source