Results 61 to 70 of about 127,528 (336)

Data on association between QRS duration on prehospital ECG and mortality in patients with confirmed STEMI

Data in Brief, 2017
Data presented in this article relates to the research article entitled “Association between QRS duration on prehospital ECG and mortality in patients with suspected STEMI” (Hansen et al., in press) [1].Data on the prognostic effect of automatically ...
Rikke Hansen, Martin Frydland, Ole Kristian Møller-Helgestad, Matias Greve Lindholm, Lisette Okkels Jensen, Lene Holmvang, Hanne Berg Ravn, Jesper Kjærgaard, Christian Hassager, Jacob Eifer Møller   +9 more
doaj   +1 more source

Expanding benefits from cardiac resynchronization therapy to exercise‐induced left bundle branch block in advanced heart failure

ESC Heart Failure, 2020
Indications of cardiac resynchronization therapy (CRT) do not include exercise‐induced left bundle branch block, but functional impairment could be improved with CRT in such cases.
Fernando L. Scolari, Anderson D. Silveira, Willian R. Menegazzo, Ana Paula Chedid Mendes, Maurício Pimentel, Nadine Clausell, Livia A. Goldraich   +6 more
doaj   +1 more source

Left Bundle Branch Pacing in Transthyretin Cardiac Amyloidosis and Alternating Bundle Branch Block

JACC: Case Reports, 2020
Progressive conduction system disease affects patients with transthyretin cardiac amyloidosis, often requiring permanent pacing as the His-Purkinje system is affected. We present a case of left bundle branch pacing in a patient with transthyretin cardiac
Taha Ahmed, MD, Samra Haroon Lodhi, MBBS, Hassan Lak, MD, Jae Lee, MD, Mazen Hanna, MD, Roy Chung, MD   +5 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Left Bundle Branch Pacing

JACC: Case Reports, 2020
His bundle pacing was developed while seeking a physiological alternative to biventricular cardiac resynchronization therapy. However, His bundle pacing may not be adequate in all patients.
Margarida Pujol-López, MD, Eduard Guasch, MD, PhD, Rafael Jiménez-Arjona, MD, Rodolfo San Antonio, MD, Lluís Mont, MD, PhD, José M. Tolosana, MD, PhD   +5 more
doaj   +1 more source

Sudden unexpected improvement in the atrioventricular conduction. What is the mechanism?

Indian Pacing and Electrophysiology Journal, 2021
The 12-lead electrocardiogram (ECG) of a 79-year-old male patient with recurrent pre-syncope showed irregular sinus rhythm with constant PR interval and left bundle branch block (LBBB) with intermittently blocked P waves. The beat following the blocked P
Anunay Gupta, Kartikeya Bhargava, Dinkar Bhasin, Sourabh Agstam, Hermohander Singh Isser   +4 more
doaj   +1 more source

Endocardial ablation of ventricular ectopic beats arising from the basal inferoseptal process of the left ventricle [PDF]

, 2018
Background Idiopathic ventricular ectopy (VE) shows predilection to sites within the left ventricular (LV) base such as the outflow tract/aortic sinuses, LV summit, and areas adjacent to the aortomitral continuity.
Anderson, RH, Bradfield, JS, Li, A, Saba, MM, Shivkumar, K, Ward, DE, Zarif, JK, Zuberi, Z   +7 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Left Bundle Branch Conduction Recovery Following Left Bundle Branch Pacing in a Heart Failure Patient

JACC: Case Reports, 2019
This report presents the application of left bundle branch pacing as a cardiac resynchronization therapy in a patient with systolic heart failure and complete left bundle branch block.
Weiwei Zhang, MD, Jingjuan Huang, MD, PhD, Yiding Qi, MS, Xuerui Shi, MS, Fei Wang, MS, Xiaohong Zhou, MD, Ruogu Li, MD, PhD   +6 more
doaj   +1 more source