Results 91 to 100 of about 315,766 (302)

Application of generalized differential quadrature method to nonlinear bending analysis of a single SWCNT over a bundle of nanotubes

open access: yesArchives of Mechanics, 2012
The deformation of an individual single walled carbon nanotube (SWCNT) over a bundle of nanotubes has been studied using the generalized differential quadrature (GDQ) method.
A. Fereidoon, A.M. Babaee, Y. Rostamiyan
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Avaliação da conformidade de cuidados que integram um bundle de prevenção da pneumonia associada à ventilação mecânica em unidade de terapia intensiva [PDF]

open access: yes, 2013
Dissertação (mestrado profissional) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação Multidisciplinar em Saúde, Florianópolis, 2013.A Pneumonia Associada à Ventilação Mecânica (PAV) é uma das infecções ...
Silva, Sabrina Guterres de
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Adherence to Staphylococcus aureus Bacteremia Management Recommendations Before, During, and After the COVID-19 Pandemic: Prognostic Implications

open access: yesAntibiotics
Background/Objectives: This work aims to assess the evolution in the management of Staphylococcus aureus bacteremia (SAB) and the impact of the COVID-19 pandemic on it.
Elizabeth Lorenzo-Hernández   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A National Collaborative Project to Decrease Healthcare-Associated Infections in Intensive Care Units: Results from Stop Hospital Infection, in Portugal

open access: yesAntibiotics
Objectives: The collaborative “Stop Hospital Infection 2.0”, implemented in Portugal between 2023 and 2025, aimed to reduce the incidence of catheter-associated urinary tract infection (CAUTI), ventilator-associated pneumonia (VAP) and central-line ...
Rui Malheiro   +6 more
doaj   +1 more source

What is A Care Bundle?

open access: yesFlorence Nightingale Journal of Nursing, 2017
The care bundle is an explicit tool with clear parameters. A care bundle usually consists of a group of between three and five evidence-based interventions.
Yazile Sayın
doaj   +1 more source

An evidence-based bundle improves the quality of care and outcomes of patients with candidaemia

open access: yes, 2020
Publisher Copyright: © 2020 The Author(s) 2019. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.Background: Candidaemia
GEMICOMED (SEIMC) and the Spanish CANDI-Bundle Group
core   +1 more source

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