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Healthcare-associated infections. [PDF]

GMS Hyg Infect Control
Healthcare-associated infections (HAIs) continue to be a leading cause of morbidity, mortality, and increased healthcare costs worldwide. Despite advances in infection prevention, the burden of HAIs remains high, exacerbated by the rise of antimicrobial resistance (AMR) and the growing complexity of patient care.
Anand G, Lahariya R.
europepmc   +7 more sources

First national point prevalence survey of healthcare-associated in-fections and antimicrobial use in acute care hospitals in the Republic of Moldova

One Health & Risk Management, 2022
Introduction. HAIs present a major public health problem with an impact on morbidity, mortality and quality of life. The objective of the study was to highlight the problem of HAIs and AM use, identification of risk factors and raising awareness of the ...
Ecaterina BUSUIOC, Natalia CATERINCIUC
doaj   +3 more sources

Using patients’ observations to evaluate healthcare workers’ alcohol-based hand rub with Pulpe’friction audits: a promising approach?

GMS Hygiene and Infection Control, 2023
Background: Hand hygiene plays an important role in the transmission of nosocomial infections from healthcare workers (HCW) to patients. Patients could play a key role in improving hand hygiene by sharing their experience of the HCW’s practices.
Velardo, Fanny, Péfau, Muriel, Nasso, Raymond, Parneix, Pierre, Venier, Anne-Gaëlle   +4 more
doaj   +1 more source

Biofilms harbour Clostridioides difficile, serving as a reservoir for recurrent infection

npj Biofilms and Microbiomes, 2021
C. difficile infection (CDI) is a worldwide healthcare problem with ~30% of cases failing primary therapy, placing a burden on healthcare systems and increasing patient morbidity. We have little understanding of why these therapies fail.
Charmaine Normington, Ines B. Moura, Jessica A. Bryant, Duncan J. Ewin, Emma V. Clark, Morgan J. Kettle, Hannah C. Harris, William Spittal, Georgina Davis, Matthew R. Henn, Christopher B. Ford, Mark H. Wilcox, Anthony M. Buckley   +12 more
doaj   +1 more source

Antimicrobial Resistance in England 2017 to 2021 (ESPAUR Report 2021–22)

Medical Sciences Forum, 2023
The English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) antimicrobial resistance (AMR) chapter reports on bacterial, viral, and fungal AMR trends between 2017 and 2021 in England.
Rebecca Guy, Hannah Higgins, Jamie Rudman, Holly Fountain, Kirsty F. Bennet, Katie L. Hopkins, Alicia Demirjian, Sarah M. Gerver, Mariyam Mirfenderesky, Katherine L. Henderson   +9 more
doaj   +1 more source

Investigating the burden of antibiotic resistance in ethnic minority groups in high-income countries: protocol for a systematic review and meta-analysis

Systematic Reviews, 2017
Background Antibiotic resistance (ABR) is an urgent problem globally, with overuse and misuse of antibiotics being one of the main drivers of antibiotic-resistant infections.
Hannah Lishman, Paul Aylin, Vivian Alividza, Enrique Castro-Sanchez, Anuja Chatterjee, Victor Mariano, Alan P. Johnson, Samir Jeraj, Céire Costelloe   +8 more
doaj   +1 more source

The epidemiology of carbapenem resistance in Acinetobacter baumannii complex in Germany (2014–2018): an analysis of data from the national Antimicrobial Resistance Surveillance system

Antimicrobial Resistance and Infection Control, 2021
Background Carbapenem-resistant Acinetobacter baumannii complex (CRABC) has globally emerged as a serious public health challenge. This study aimed to describe epidemiological trends and risk factors of carbapenem resistance in A.
Dunja Said, Niklas Willrich, Olaniyi Ayobami, Ines Noll, Tim Eckmanns, Robby Markwart   +5 more
doaj   +1 more source

The epidemiology of carbapenem-non-susceptible Acinetobacter species in Europe: analysis of EARS-Net data from 2013 to 2017

Antimicrobial Resistance and Infection Control, 2020
Background Due to limited therapeutic options and their association with high mortality and morbidity, carbapenem-non-susceptible Acinetobacter spp. (CNA) are of significant public health importance.
Olaniyi Ayobami, Niklas Willrich, Beneditta Suwono, Tim Eckmanns, Robby Markwart   +4 more
doaj   +1 more source

Molecular diagnostics in South Africa and challenges in the establishment of a molecular laboratory in developing countries

Journal of Infection in Developing Countries, 2020
The laboratory plays a significant role in public health surveillance, outbreak investigation and infection prevention and control strategies. Microbiology laboratories are moving towards incorporating molecular biology techniques for the surveillance ...
Ashika Singh-Moodley, Husna Ismail, Olga Perovic   +2 more
doaj   +1 more source

In Vitro Antifungal Activity of Manogepix and Other Antifungal Agents against South African Candida auris Isolates from Bloodstream Infections

Microbiology Spectrum, 2022
We determined the susceptibility of South African Candida auris bloodstream surveillance isolates to manogepix, a novel antifungal, and several registered antifungal agents. C. auris isolates were submitted to a reference laboratory between 2016 and 2017.
Tsidiso G. Maphanga, Ruth S. Mpembe, Serisha D. Naicker, Nelesh P. Govender   +3 more
doaj   +1 more source