Results 121 to 130 of about 315,766 (302)
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Mixed-joint or Mixed-Leader Bundle? The Framing Effects of Price Discount on Bundle Evaluations
Marketing Management Journal, 2006 This research tests the framing effects of bundle price discount on consumer evaluations of a bundle. Drawing upon attribution theory, this article investigates consumers' diversified responses to a mixed-joint and a mixed-leader bundle with an ...
SHIBIN SHENG
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
, 2014 <p>API for building researchobject.org RO bundles.</p> <p>Complies with RO bundle specification version 1.0.</p> <p>This API is built on the Java 7 NIO Files and uses the Java 7 ZIP file provider to generate the RO Bundle.&
Stian Soiland-Reyes (80636) +1 more
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Ventilator-associated pneumonia: Epidemiological changes or disregarded bundles?
Open Health, 2023 Frontera Regina, Barone Mirko
doaj +1 more source
Journal of the London Mathematical Society, 1996 Just as $\Cstar$ principal bundles provide a geometric realisation of two-dimensional integral cohomology; gerbes or sheaves of groupoids, provide a geometric realisation of three dimensional integral cohomology through their Dixmier-Douady class. I consider an alternative, related, geometric realisation of three dimensional cohomology called a bundle ...
openaire +4 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
AntibioticsBackground: Dedicated bundles were proven to reduce CLABSIs in a neonatal intensive care unit (NICU). Methods: We performed an observational pre–post study to evaluate the impact of a bundle for CLABSI prevention in our NICU. All umbilical vein catheters
Chiara Poggi +8 more
doaj +1 more source