Results 131 to 140 of about 1,098,643 (378)

Microtubule bundling [PDF]

Nature, 1990
S A, Lewis, N, Cowan
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Experimental determination and analysis of the transverse pressure difference in a wire-wrapped rod bundle

, 2021
Mason Childs, Rodolfo Vaghetto, P. Jones, Nolan Goth, Yassin A. Hassan   +4 more
openalex   +2 more sources

Parabolic Higgs bundles and \(\Gamma\)-Higgs bundles [PDF]

, 2013
Let \(Y\) be a smooth projective variety and \(\Gamma\) a finite group acting faithfully on \(Y\), so that the quotient variety \(X=\Gamma\backslash Y\) is also smooth and the projection \(\pi:Y\to X\) is a Galois covering with Galois group \(\Gamma\).
BISWAS, INDRANIL, MAJUMDER, SOURADEEP, WONG, MICHAEL LENNOX   +2 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Discrete C*-coactions and C*-algebraic bundles [PDF]

, 1996
John Quigg
openalex   +1 more source

Parabolic bundles as orbifold bundles

Duke Mathematical Journal, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Ventilator-associated pneumonia: Epidemiological changes or disregarded bundles?

Open Health, 2023
Frontera Regina, Barone Mirko
doaj   +1 more source