Results 181 to 190 of about 817,701 (334)

Analysis of ECG and VCG by Means of Reconstruction Method : EFFECT OF THE HEART POSITION ON ECG AND VCG IN BUNDLE BRANCH BLOCK COMPLICATED BY MYOCARDIAL INFARCTION.

, 1958
Hiroshi Kato
openalex   +2 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Effect of acute kidney injury care bundles on patient prognosis: a systematic review and meta-analysis. [PDF]

BMC Nephrol
Huang Y, Guan L, Sun C.
europepmc   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Parallelisability of Principal Fibre Bundles [PDF]

, 1949
Shiing-Shen Chern, Sze-Tsen Hu
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

IDC-IMPROVE: protocol for a cluster randomised feasibility trial of a care bundle to improve indwelling catheter care (IDC) in residential aged care homes in Australia. [PDF]

Pilot Feasibility Stud
Ostaszkiewicz J, Gilbert AS, Tay C, Watt E, Barry D, Taylor W, Cecil J, Cockerell R, Crowe H, Lau L, Murray M, Nakrem S, Paterson C, Peters M, Sahay A, Sweeney A, Thompson J, Westaway J, Bower W, Christina J, Zana A, Batchelor F.   +21 more
europepmc   +1 more source

Electrocardiogram and Vectorcardiogram in Right Ventricular Hypertrophy and Right Bundle-Branch Block

, 1957
William R. Milnor, Charles Bertrand, Frederick Mugler   +2 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Case Report: Left bundle branch area pacing in cardiac resynchronization therapy increases conduction velocity. [PDF]

Front Cardiovasc Med
Zhang W, Wang L, He C, Ding C.
europepmc   +1 more source