Results 111 to 120 of about 167,623,224 (301)

Multiple intracardiac recordings in evaluation of patterns occurring during attempted his bundle pacing in man

, 1978
The various patterns resulting from stimulation through the catheter electrodes recording His bundle activity were evaluated in 30 patients using intracardiac electrograms from the right ventricular apex (RVA), posterosuperior wall of the left ventricle (
Castellanos, Agustin, Mallon, Stephen M, Sung, Ruey J, Mendoza, Ivan J, Myerburg, Robert J   +4 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Experience with transvenous lead extraction of His bundle pacing leads [PDF]

Background: Nowadays, we observe a growing interest in conduction system pacing (CSP). Therefore, we expect the number of patients with CSP to increase significantly in the coming years.
Ulman, Mateusz; Department of Electrocardiology, The John Paul II Hospital, Kraków, Poland, Boczar, Krzysztof; Department of Electrocardiology, The John Paul II Hospital, Kraków, Poland, Lelakowski, Jacek; Department of Electrocardiology, The John Paul II Hospital, Kraków, Poland; Institute of Cardiology, Jagiellonian University Medical College, Kraków, Poland, Gajek, Jacek; Medical Faculty, Wroclaw University of Science and Technology, Wrocław, Poland, Ząbek, Andrzej; Department of Electrocardiology, The John Paul II Hospital, Kraków, Poland; Institute of Cardiology, Jagiellonian University Medical College, Kraków, Poland, Sławuta, Agnieszka; Department of Cardiology, Klodzko County Hospital, Kłodzko, Poland, Ciesielski, Adam; Department of Cardiology, Multidisciplinary Public Hospital, Nowa Sól, Poland, Dębski, Maciej; Norwich Medical School, University of East Anglia, Norwich, United Kingdom, Golińska-Grzybała, Karolina; Department of Noninvasive Cardiovascular Laboratory, John Paul II Hospital, Kraków, Poland   +8 more
core   +1 more source

Output‐dependent His bundle pacing: Unexpected His‐Purkinje system pathology unmasking

Annals of Noninvasive Electrocardiology
The anatomy of the His‐Purkinje system has been studied, yet there remains a knowledge gap regarding the impact of His bundle pacing and its electrocardiographic implications.
Ronpichai Chokesuwattanaskul, Noppachai Siranart, Krit Jongnarangsin   +2 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Data for: Restitution Characteristics of His Bundle and Working Myocardium in Isolated Rabbit Hearts

, 2019
The Purkinje system (PS) and the His bundle have been recently implicated as an important driver of the rapid activation rate after 1-2 minutes of ventricular fibrillation (VF).
Huang, Liqun, Panitchob, Nuttanont, Dosdall, Derek, Hu, Nan, Huang, Shangwei, Ranjan, Ravi   +5 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source