Results 91 to 100 of about 56,979 (258)

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Effect of His Bundle Pacing on Abnormal Myocardial Fatty Acid and Glucose Metabolism Induced by Right Ventricular Pacing

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Metabolic disorder is noted for pacing‐induced cardiomyopathy. The benefits of His bundle pacing over right ventricular (RV) pacing in preventing pacing‐induced cardiomyopathy from a metabolic perspective are yet to be fully understood. Method
Yu‐Sheng Lin, Huang‐Chung Chen, Wei‐Chieh Lee, Wan‐Chun Ho, Shun‐Fu Chang, Yung‐Lung Chen, Teng‐Yao Yang, Mien‐Cheng Chen   +7 more
doaj   +1 more source

The constellation of His-bundle pacing [PDF]

European Heart Journal - Case Reports, 2020
Álvaro Arce León, María Teresa Moraleda Salas, Juan Manuel Fernández Gómez, Pablo Moriña Vázquez   +3 more
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Overcoming left bundle branch block by permanent His bundle pacing: Evidence of longitudinal dissociation in the His via recordings from a permanent pacing lead

HeartRhythm Case Reports, 2017
Parikshit S. Sharma, MD, MPH, FACC, Kristin Ellison, MD, Hena N. Patel, MD, Richard G. Trohman, MD, MBA   +3 more
doaj   +1 more source

Comparison of Left Ventricular Function after His Bundle Pacing vs Left Bundle Branch Area Pacing Implantation

Majalah Kardiologi Indonesia
Background: Right ventricular pacing may lead to deterioration of left ventricular (LV) function. Recent guideline suggests the use of conduction system pacing (CSP) with either his bundle pacing (HBP) or left bundle branch area pacing (LBBAP).
Kurniawan Prakoso, Kevin Wibawa, Giky Karwiky, Mohammad Rizki Akbar, Januar Wibawa Martha, Mohammad Iqbal   +5 more
doaj   +1 more source

Bundle branch reentry with His dissociation—The His bundle: Bystander or participant? [PDF]

HeartRhythm Case Reports, 2018
Maged F. Nageh, Jacqueline Schwartz, Rasoul Mokabberi, Devin Dabiesingh, Nareg Kalamkarian   +4 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

bundle of His

Citation: 'bundle of His' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10481 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source