Results 71 to 80 of about 346,759 (289)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Tannakian interpretation of the elliptic infinitesimal braid Lie algebras

open access: yes, 2017
Let $n\geq 1$. The pro-unipotent completion of the pure braid group of $n$ points on a genus 1 surface has been shown to be isomorphic to an explicit pro-unipotent group with graded Lie algebra using two types of tools: (a) minimal models (Bezrukavnikov),
Enriquez, Benjamin, Etingof, Pavel
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Determination of the bundle price for digital information goods [PDF]

open access: yes, 2003
The fast emergence of Internet as a media to distribute digital information goods created many new opportunities for the packaging and pricing of these goods. The pricing of information goods introduces a challenge since the cost structure of information
Karabulut, Kaan   +2 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Early Deterioration of the Right Ventricular Pacing Threshold Predicts the Increase in His‐Bundle Pacing Threshold During the Chronic Phase: A Single‐Center Retrospective Study

open access: yesJournal of Arrhythmia
Background His‐bundle pacing (HBP) facilitates physiological ventricular activation. However, concerns about long‐term threshold deterioration persist. The predictors of chronic threshold elevation are not yet well established.
Kenji Baba   +6 more
doaj   +1 more source

Nurowski's conformal structures for (2,5)-distributions via dynamics of abnormal extremals

open access: yes, 2006
As was shown recently by P. Nurowski, to any rank 2 maximally nonholonomic vector distribution on a 5-dimensional manifold M one can assign the canonical conformal structure of signature (3,2).
Agrachev, Andrei, Zelenko, Igor
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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