Results 141 to 150 of about 57,705 (306)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Supraventricular Tachycardias Using Multiple Accessory Pathways. [PDF]

J Arrhythm
Yamada T.
europepmc   +1 more source

Bundle of His electrograms in congenital corrected transposition of the great arteries. A study of two adult cases. [PDF]

, 1973
H S Friedman, Janusz Lipski, John Pantazopoulos, Gabriel Genkins, E Donoso   +4 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Electrocardiographic Diagnosis of Acute Myocardial Ischemia During His Bundle Pacing

Anatolian Journal of Cardiology, 2022
Leonardo Marinaccio, Francesco Vetta, Giuliana Ginocchio, Giuseppe Maria Marchese, Domenico Marchese   +4 more
doaj   +1 more source

Atrioventricular Delay Optimization in His-Optimized Cardiac Resynchronization Therapy: A Case Report. [PDF]

Clin Case Rep
Nguyen Quang M, Kieu Ngoc D, Nguyen Khac Le S, Tran Le Uyen P, Nguyen Tri T.   +4 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Left Bundle Branch Pacing for Cardiac Resynchronization Therapy: Nonrandomized On-Treatment Comparison With His Bundle Pacing and Biventricular Pacing

, 2020
Shengjie Wu, Lan Su, Pugazhendhi Vijayaraman, Rujie Zheng, Mengxing Cai, Lei Xu, Ruiyu Shi, Zhouqing Huang, Zachary I. Whinnett, Weijian Huang   +9 more
openalex   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Atrioventricular Junction Ablation with High-Definition Recording of Atrioventricular Node Potential. [PDF]

J Cardiovasc Dev Dis
Matteucci A, Maggio E, Dardani D, Russo M, Galeazzi M, Nardi F, Fedele S, Pandozi C, Colivicchi F.   +8 more
europepmc   +1 more source